Bone metastasis after breast cancer surgery
Conditions
Interventions
Exposure group:Wenshen Zhuanggu Formula Combined with Western Medicine (Zoledronic Acid/Disuzumab)
Non-exposed group:Simple Western Medicine Treatment (Zoledronic Acid/Disuzumab)
Sponsors
Longhua Clinical Medical College affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Those who meet the following conditions shall be included: (1) It meets the diagnostic criteria of breast cancer and must be confirmed by pathology; (2) Bone metastases must be confirmed by whole body bone scanning (ECT), X-ray, CT, MRI or bone pathological biopsy; (3) There is no second primary tumor in the whole body; (4) All patients are female, aged =18 years and =70 years; (5)The required clinical data are complete, and the information of symptoms, signs and tongue and pulse in traditional Chinese medicine is complete enough for syndrome differentiation; (6)Physical condition Karnofsky>40 points, and it is expected to survive for more than 6 months; (7)The patient agrees and cooperates with the investigation;
Exclusion criteria
Exclusion criteria: Exclusion criteria: those who meet the selection criteria but meet one of the following conditions shall be excluded: (1) the diagnosis is not in line with breast cancer or without bone metastasis; (2) Patients with severe heart, liver, kidney, blood system, endocrine system dysfunction and mental illness; (3) Patients with other organ metastases; (4) The patient is accompanied by SREs; (5) The patient's clinical data is not perfect, or the information of the four diagnoses of traditional Chinese medicine is incomplete; (6) The patient does not cooperate; (7) Participated in clinical trials of other drugs within 12 weeks before screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concise pain scale;Pain score by SF-MPQ method; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of curative effect of bone metastases;Progressively free survival;Incidence rate of bone adverse events;Quality of life score; | — |
Countries
China
Contacts
Public ContactChunyu Wu
Longhua Hospital, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed