Asthma-COPD Overlap
Conditions
Interventions
Basic treatment + Kidney-Strengthening and Asthma-Preventing Tablets:ICS/LABA/LAMA + Tonifying Kidney and Preventing Asthma Tablets
2) Basic treatment + Shenxiang Anti-Cough Tablets (placebo):ICS/LABA/LAMA + Tonifying Kidney and Preventing Asthma Tablets placebo
Sponsors
Kashi City People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Age range: 40 years old to 85 years old (gender not restricted); 1) Weight range: 45 kilograms to 85 kilograms; 2) According to diagnostic criteria, those meeting the ACO criteria; 3) Stable patients without significant worsening of cough or expectoration symptoms; 4) Pulmonary function test results meeting the moderate and severe obstruction criteria of 30 = FEV1%pred < 80; 5) Patients diagnosed with the syndrome of lung and kidney deficiency by traditional Chinese medicine; 6) Without cognitive, speech disorders or mental system diseases, and able to cooperate with the completion of the clinical study; 7) Participants voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Exclude patients with other severe diseases of the lungs, heart, liver, kidneys and blood system (such as pulmonary heart disease, malignant tumors, respiratory failure and pneumothorax, etc.). 2) Patients with severely impaired heart, liver, kidney functions: cardiac function grade 3-4, ALT and/or AST exceeding 1.5 times the upper limit of normal, and Cr exceeding the upper limit of normal. 3) Exclude patients in the acute exacerbation stage of chronic obstructive pulmonary disease. 4) Pregnant or planning to become pregnant, lactating women. 5) Patients using concomitant medications, especially those that have a significant impact on the test drug, affecting the judgment of its efficacy and safety. 6) Those who participated in other clinical studies within the previous 4 weeks. 7) Other situations that the investigator deems unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ACT(Asthma Control Test);CAT(COPD Assessment Test); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary function;mMRC;Quantitative scoring of TCM syndromes;Acute exacerbation situation; | — |
Countries
CHINA
Contacts
Public ContactJingcheng Dong
Fudan University Institute of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed