Irritable Bowel Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The patient voluntarily participated and signed the informed consent form. 2. The age range is from 18 to 65 years old. 3. According to the Rome IV diagnostic criteria, it is diagnosed as diarrhea.
Exclusion criteria
Exclusion criteria: 1. Patients with organic gastrointestinal disorders; 2. Those with a history of abdominal or pelvic surgeries; 3. Those with chronic pancreatitis, tumors, peptic ulcers, tuberculous peritonitis, chronic liver diseases, liver cirrhosis, etc. (non-gastrointestinal digestive system diseases); 4. Those with abnormal fecal routine examination (positive for occult blood, red blood cells, or white blood cells); 5. Those with severe diseases of important organs such as heart, lungs, kidneys, immune regulation disorders, metabolic diseases, malignant tumors or reproductive system diseases such as ovarian cysts, endometriosis, etc.; 6. Those with significantly abnormal laboratory test indicators; 7. Patients with severe mental disorders, or those with a Hamilton Depression Scale (HAMD) score > 20 points, or a Hamilton Anxiety Scale (HAMA) score > 29 points; 8. Those who mainly experienced nocturnal abdominal pain before screening, or had unexplained weight loss, fever, jaundice, bloody stool/black stool, or BMI = 17; 9. Those with a history of drug abuse or alcoholism; 10. Those who cannot stop using drugs that affect gastrointestinal motility and function during the trial (such as antibiotics, microecological preparations, proton pump inhibitors, etc.); 11. Pregnant women, lactating women, or those planning to become pregnant during the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical total effective rate;Score of the IBS Symptom Severity Scale (IBS-BSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life Assessment;Improvement in mental state;Overall symptom score; | — |
Countries
China
Contacts
Xianning Central Hospital