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A Multimodal Study on Exploring Chinese Medicine External Therapies for Cancer Anorexia-Cachexia Syndrome Based on the Principle of 'Nei-Wai Yi Li' (Internal and External Unity).

A Multimodal Study on Exploring Chinese Medicine External Therapies for Cancer Anorexia-Cachexia Syndrome Based on the Principle of 'Nei-Wai Yi Li' (Internal and External Unity).

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000739
Enrollment
Unknown
Registered
2026-03-25
Start date
2026-01-09
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer anorexia-cachexia syndrome

Interventions

Control Group:Routine nutritional support therapy is administered, with the addition of Sanxiang Qútie simulated patches applied to the Shenque acupoint, with each patch applied for 6-8 hours.
Treatment group:Routine nutritional support therapy, combined with the application of Sanxiang to the Shenque acupoint, each patch applied for 6-8 hours.

Sponsors

Jiangsu Province Integrated Chinese and Western Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Meets diagnostic criteria for malignant tumors; 2) Meets diagnostic criteria for CACS: unintentional weight loss >5% in the past 6 months; weight loss >2% when BMI 2% when muscle mass reduction is present. Any of the above conditions combined with anorexia or systemic inflammation is sufficient (Anorexia assessment: Functional Assessment of Anorexia/Cachexia Therapy - Appetite (FAACT-A/CS) score =37 points; Inflammation assessment: C-reactive protein (CRP) >5 mg/L); 3) Age =18 years and =85 years, expected survival period greater than 3 months, Karnofsky Performance Status (KPS) score >60; 4) Voluntarily signed the informed consent and strictly adhered to the predetermined intervention protocol.

Exclusion criteria

Exclusion criteria: 1) Patients with planned surgery within 21 days of enrollment; 2) Patients with acute infections (e.g., respiratory, urinary, or skin/soft tissue infections) within 1 week prior to enrollment; 3) Patients with clinically significant ascites (e.g., abdominal distension, positive shifting dullness); 4) Patients who have received head and neck radiation therapy within 3 months prior to enrollment; 5) Patients who have undergone radical total gastrectomy for gastric cancer; 6) Patients with confirmed tumor-related mechanical bowel obstruction by imaging studies; 7) Patients who are unable to follow the study protocol as required.

Design outcomes

Primary

MeasureTime frame
Appetite Assessment Numerical Rating Scale;

Secondary

MeasureTime frame
Body Mass Index;Both hands grip strength;Prealbumin;Albumin;C-reactive protein;

Countries

China

Contacts

Public ContactXing Haiyan

Jiangsu Province Integrated Chinese and Western Medicine Hospital

2057574584@qq.com13701455246

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026