Cancer anorexia-cachexia syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Meets diagnostic criteria for malignant tumors; 2) Meets diagnostic criteria for CACS: unintentional weight loss >5% in the past 6 months; weight loss >2% when BMI 2% when muscle mass reduction is present. Any of the above conditions combined with anorexia or systemic inflammation is sufficient (Anorexia assessment: Functional Assessment of Anorexia/Cachexia Therapy - Appetite (FAACT-A/CS) score =37 points; Inflammation assessment: C-reactive protein (CRP) >5 mg/L); 3) Age =18 years and =85 years, expected survival period greater than 3 months, Karnofsky Performance Status (KPS) score >60; 4) Voluntarily signed the informed consent and strictly adhered to the predetermined intervention protocol.
Exclusion criteria
Exclusion criteria: 1) Patients with planned surgery within 21 days of enrollment; 2) Patients with acute infections (e.g., respiratory, urinary, or skin/soft tissue infections) within 1 week prior to enrollment; 3) Patients with clinically significant ascites (e.g., abdominal distension, positive shifting dullness); 4) Patients who have received head and neck radiation therapy within 3 months prior to enrollment; 5) Patients who have undergone radical total gastrectomy for gastric cancer; 6) Patients with confirmed tumor-related mechanical bowel obstruction by imaging studies; 7) Patients who are unable to follow the study protocol as required.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Appetite Assessment Numerical Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index;Both hands grip strength;Prealbumin;Albumin;C-reactive protein; | — |
Countries
China
Contacts
Jiangsu Province Integrated Chinese and Western Medicine Hospital