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Risk factor analysis and predictive model construction for chronic atrophic gastritis with intestinal metaplasia based on the integration of disease and syndrome.

Risk Factor Analysis and Predictive Model Construction for Chronic Atrophic Gastritis with Intestinal Metaplasia Based on Syndrome and Disease Combination Approach

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2026000706
Enrollment
Unknown
Registered
2026-03-24
Start date
2026-02-15
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic atrophic gastritis with intestinal metaplasia

Interventions

Observation group:"Completion of the 'Survey Questionnaire on Risk Factors and Traditional Chinese Medicine Syndromes in Chronic Atrophic Gastritis with Intestinal Metaplasia'"

Sponsors

Fujian University of Traditional Chinese Medicine Affiliated Second People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion Criteria for the Group with Chronic Atrophic Gastritis and Intestinal Metaplasia (1) Meets the aforementioned diagnostic criteria; (2) Confirmed by electronic gastroscopy and histopathological examination as having chronic atrophic gastritis with intestinal metaplasia prior to enrollment; (3) Age between 18-75 years, no restriction on gender; (4) Possesses reading ability, can independently complete the questionnaire, and sign the informed consent form; 2. Inclusion Criteria for the Group with Chronic Superficial Gastritis (1) Meets the aforementioned diagnostic criteria; (2) Confirmed by electronic gastroscopy and histopathological examination as having chronic superficial gastritis prior to enrollment; (3) Age between 18-75 years, no restriction on gender; (4) Possesses reading ability, can independently complete the questionnaire, and sign the informed consent form;

Exclusion criteria

Exclusion criteria: (1) Gastric cancer and cases where clinical diagnosis has already considered metastasis from other tumors to the stomach; (2) Patients who have undergone previous gastric surgical treatments, ESD (Endoscopic Submucosal Dissection), or EMR (Endoscopic Mucosal Resection); (3) Pathological diagnosis with concurrent dysplasia; (4) Pregnant and breastfeeding women; (5) Patients with severe primary diseases of the cardiovascular, hepatic, renal, or other systems.

Design outcomes

Primary

MeasureTime frame
Disease risk factors - Family history - Family history of stomach cancer;Gastrointestinal history - Chronic atrophic gastritis;Dietary habits - Dietary preferences;Dietary habits - Dietary habits;Lifestyle habits - Smoking;Lifestyle habits - Drinking;Lifestyle habits - Staying up late;Lifestyle habits - lack of exercise;Auxiliary examination - Endoscopic findings;Auxiliary examination - Histopathology - Atrophy;Auxiliary examination - Histopathology - Intestinal metaplasia;Auxiliary examination - Histopathology - Chronic inflammation;Auxiliary examination - Histopathology - Active inflammation;Four-Method Diagnostic Information - Principal Symptom - Epigastric Pain;Four Diagnostic Methods Information - Principal Symptom - Epigastric Fullness;Four Diagnostics Information - Principal Symptoms - Epigastric Distension and Fullness;Four Diagnostic Information - Principal Symptoms - Pain behind the sternum;Four Diagnostic Information - Chief Complaint - Burning sensation behind the sternum;Four Diagnostic Information - Principal Symptoms - Heartburn;Four Examinations - Chief Complaint - Acid Regurgitation;Four Diagnostic Information - Chief Complaint - Abdominal Distension;Four Diagnostic Information - Chief Complaint - Abdominal Pain;Four Diagnostics Information - Chief Complaint - Belching;

Secondary

MeasureTime frame
Disease risk factors - Family history - Family history of other gastrointestinal tumors;Gastrointestinal history - Cholecystectomy;Gastrointestinal history - Gastroesophageal reflux disease;Gastrointestinal history - Gastric ulcer;Gastrointestinal history - Duodenal ulcer;Gastrointestinal history - Hp infection;Auxiliary examination - Histopathology - Helicobacter pylori infection;Four Diagnostic Methods Information - Secondary Symptoms - Sensation of Foreign Body in Throat;Four Diagnostic Methods Information - Secondary Symptoms - Dry Mouth;Four Diagnostic Information - Secondary Symptoms - Bitter Taste in Mouth;Four Diagnostics - Secondary Symptoms - Halitosis;Four Diagnostic Methods Information - Secondary Symptoms - Mouth and Tongue Ulcers;Four Diagnostic Information - Secondary Symptoms - Nausea;Four Diagnostic Information - Secondary Symptoms - Vomiting;Four Diagnostic Methods Information - Secondary Symptoms - Irritable and Easily Annoyed;Four-Method Diagnostic Information - Secondary Symptoms - Restlessness;Four Diagnostic Information - Secondary Symptoms - Poor Appetite;Four Diagnostic Information - Secondary Symptoms - Mental Fatigue;Four Diagnostic Methods Information - Secondary Symptoms - Coldness in the limbs;Four Diagnostic Methods Information - Secondary Symptoms - Fatigue and Weakness;Four Diagnostic Information - Secondary Symptoms - Feeling hungry but not wanting to eat;Four Diagnostic Methods Information - Secondary Symptoms - Constipation;Four Diagnostic Methods Information - Secondary Symptoms - Loose Stools;Four Diagnostic Methods Information - Secondary Symptoms - Constipation;Four Diagnostic Methods Information - Secondary Symptoms - Diarrhea;Four Diagnostic Information - Secondary Symptoms - Stool with undigested food;Four Diagnostic Methods Information - Secondary Symptoms - Sticky Stool;Four Diagnostic Methods Information - Secondary Symptoms - Incomplete Bowel Movement;Four Diagnostic Methods - Secondary Symptoms - Easily Awakened;Four D

Countries

China

Contacts

Public ContactZeng Shiqi

Fujian University of Traditional Chinese Medicine Affiliated Second People's Hospital

18065031358@163.com18065031358

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026