Artificial ulcer
Conditions
Interventions
Control Group:Oral esomeprazole magnesium enteric-coated dry suspension (BEMEI Pharmaceutical Co., Ltd., Shenzhen, National Medical Products Administration Approval No. HJ20233134), 20 mg twice dail
Treatment Group:In addition to the treatment for the control group, patients were also administered the modified Banxia Xiexin Decoction.
Sponsors
Lishui Hospital of Traditional Chinese Medicine affiliated to Zhejiang University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age: 18-75 years old; (2) Diagnosed with early esophageal cancer, gastric cancer or precancerous lesions through gastroscopy and pathology, and successfully underwent ESD surgery; (3) Postoperative gastroscopy confirmed the presence of an unclosed artificial ulcer. (4) Comply with the syndrome differentiation criteria for the mixed cold and heat type as stipulated in the "Consensus on the Integrated Traditional Chinese and Western Medicine Diagnosis and Treatment of Peptic Ulcer (2017)". (5) Sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Allergic to the research drug (a traditional Chinese medicine composed of esomeprazole and Banxia Xiexin Decoction); (2) Postoperative pathology indicates a positive resection margin or infiltration depth exceeding the submucosa; (3) Combined with severe heart, liver or kidney insufficiency; (4) Pregnant or lactating women; (5) Long-term use of non-steroidal anti-inflammatory drugs or anticoagulant drugs; (6) Combined with other severe digestive system diseases or systemic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total clinical effective rate after 8 weeks of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in TCM syndrome points;Ulcer healing rate, proportion of S2 stage healing;Average length of hospital stay and treatment cost; | — |
Countries
china
Contacts
Public Contactwu jianye
Lishui Hospital of Traditional Chinese Medicine affiliated to Zhejiang University of Chinese Medicine
Outcome results
None listed