Polycystic ovary syndrome
Conditions
Interventions
Retrospective cohort:Observational study, without intervention measures
Prospective cohort:Observational study, without intervention measures
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
21 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for polycystic ovary syndrome (as defined in the 2023 "International Evidence-Based Guidelines for the Assessment and Management of Polycystic Ovary Syndrome"); 2. Age = 21 years, patients with pregnancy needs/who are pregnant/after childbirth; 3. The completeness of case data is = 70% (core information includes: diagnostic basis, main treatment measures, at least one follow-up record); 4. Prospective cases need to sign an informed consent form (retrospective cases are exempt from informed consent, and ethical approval is required).
Exclusion criteria
Exclusion criteria: 1. The case data is severely lacking (such as without clear diagnostic basis, key diagnostic information not recorded); 2. Complicated with other serious diseases (such as advanced malignant tumors, severe liver and kidney failure) and having other endocrine diseases besides PCOS (such as adrenal tumors, tumors causing hyperandrogenism, etc.), which may interfere with the diagnosis and evaluation of polycystic ovary syndrome; 3. Infertile individuals caused by chromosomal abnormalities of both spouses, tubal factors, organic lesions of reproductive organs or male factors; 4. Prospective cases that refuse to cooperate with follow-up or are unable to provide valid contact information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pregnancy outcome;Pregnancy complications;Postpartum condition;Newborn birth data;Newborn complications;The condition of the baby; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anti-Müllerian hormone(AMH);Follicle-stimulating hormone(FSH);Luteinizing hormone(LH);Testosterone(T);Thyroid stimulating hormone(TSH);Free triiodothyronine(FT3);Free thyroxine 4-Iodoformate(FT4);Fasting blood glucose(FPG);Fasting insulin(FINS);Insulin resistance index(HOMA-IR);Blood sugar level two hours after the meal(2hPG);Insulin two hours after the meal(2hINS);Total serum cholesterol(TC);Triglyceride(TG);Low-density lipoprotein(LDL-C);High-density lipoprotein(HDL-C);Homocysteine(HCY);25-hydroxyvitamin D(25-OHD);Endometrial thickness(EM);Number of retrieved oocytes;Oocyte retrieval rate;Number of MII oocytes;MII oocyte rate;2PN number;2PN fertilization rate;Number of 2PN eggs;2PN cleavage rate;Number of high-quality embryos in D3 group;D3 high-quality embryo rate;The number of blastocysts formed;Blastocyst formation rate;The number of high-scoring blastocysts;High scoring blastocyst rate;Number of transplantable embryos;Transplantable embryo rate;The incidence rate of OHSS; | — |
Countries
China
Contacts
Public ContactLinling Wu
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed