Cervical HPV infection
Conditions
Interventions
Acupoint Insertion Thread Group:Carry out acupuncture thread implantation
The fake acupoint embedding thread group:The group that underwent fake acupuncture thread insertion
Sponsors
The Obstetrics & Gynecology Hospital of Fudan University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Visited Fudan University Affiliated Obstetrics and Gynecology Hospital from December 2025 to December 2026. 2. Diagnosed with persistent high-risk HPV infection in the cervix. Defined as: In women who have not been infected with the relevant HPV subtype before, the same HPV DNA subtype was detected for more than 2 consecutive times within a 12-month interval. 3. TCT test results were NILM or ASC-US or LSIL; and the results of the colposcopy examination conducted before enrollment were satisfactory, and no signs of suspected HSIL or more severe lesions were observed under the microscope. 4. The subjects voluntarily joined this study, signed the informed consent form, had good compliance, and cooperated with the follow-up. 5. Age = 18 years and = 70 years, with sexual life. 6. Agreed to follow the protocol of this study and practice effective contraception during the trial participation.
Exclusion criteria
Exclusion criteria: 1. The histopathological diagnosis is HSIL or above in the cervix, vagina, and vulva; 2. There are severe organ function disorders or complications; 3. Pregnant or having fertility requirements within the past half year; 4. Patients with hematological disorders or bleeding disorders; 5. Patients with acute inflammation of reproductive organs; 6. Patients with mental disorders; 7. Allergy to sutures; 8. Skin damage or infection at the suture site; 9. Patients with immune disorders; 10. Patients with severe heart disease or diabetes; 11. Patients who have had suture treatment before; 12. Those who have used glucocorticoids or immunosuppressants within the past 3 months; 13. Those who have received HPV vaccine within the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clearance rate of HR-HPV and viral load; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting-state heart rate variability;Local immune indicators of the cervix;Peripheral blood immune system;metabolic index;Psychological state and sleep indicators;security index; | — |
Countries
China
Contacts
Public ContactXin weijuan
The Obstetrics & Gynecology Hospital of Fudan University
Outcome results
None listed