Ischemic stroke
Conditions
Interventions
experimental group:electroacupuncture
control group:False electro-acupuncture
Sponsors
Fujian University of Traditional Chinese Medicine Affiliated Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meets the above criteria for diagnosing ischemic stroke; (2) Age 45 to 70 years old, gender not restricted; (3) First onset, mainly involving unilateral limb impairment; from onset to enrollment time is 7 to 14 days (based on the clear onset time or the first imaging confirmation time); vital signs are stable, and they can accept standardized rehabilitation training and MRI examination; (4) FMA-UE = 55 points or FMA-LE = 25 points, and the affected side of the upper limb or lower limb has at least the minimum voluntary movement ability (FMA-UE = 10 points or FMA-LE = 10 points), and can cooperate to complete 4-week rehabilitation training and assessment; (5) Mini-Mental State Examination (MMSE) score = 20 points, with basic cognitive comprehension and execution ability, and can cooperate to complete training and assessment; (6) The subject has signed the informed consent form; if the subject has limited signing ability, their legal representative or authorized agent signs according to regulations and attempts to obtain the subject's consent/informational cooperation; (7) Head MRI shows that the lesion is mainly located in the subcortical area (such as the internal capsule, basal ganglia area, radiating zone, etc.), and does not involve extensive motor cortex.
Exclusion criteria
Exclusion criteria: (1) Non-ischemic stroke-related diseases such as cerebral hemorrhage, brain tumors, and central nervous system infections; (2) Those rated as level 4 by the Modified Ashworth Scale (MAS); (3) Those with severe dysfunction of important organs such as severe heart, liver, or kidney failure; (4) Those with severe cognitive impairment (MMSE < 20 points), affecting cooperation in assessment and intervention; (5) Those with severe mental disorders, affecting compliance and assessors; (6) Those who have a severe fear of acupuncture, even after adequate explanation and adaptation training; (7) Those with a pacemaker installed or with clear contraindications to electro-acupuncture; (8) Those with hemorrhagic transformation shown on head MRI or with other active intracranial hemorrhage; (9) Those whose imaging assessment before randomization indicated complete structural interruption of key white matter fiber tracts; (10) Those who received systematic acupuncture or electro-acupuncture treatment within 2 weeks before enrollment (= 3 times per week or continuous treatment); (11) Those who have had a second stroke (including this one or the previous two), with obvious clinical symptoms or imaging evidence, affecting study assessment and intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Motor Function Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| National Institutes of Health Stroke Scale;Barthel Index;Traditional Chinese Medicine Syndrome Score Rating;Magnetic Resonance Diffusion Tensor Imaging; | — |
Countries
CHINA
Contacts
Public ContactGengzhao Chen
Fujian University of Traditional Chinese Medicine Affiliated Rehabilitation Hospital
Outcome results
None listed