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Clinical Efficacy of Acupuncture for Mild to Moderate Depression

Clinical Efficacy of Acupuncture for Mild to Moderate Depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000688
Enrollment
Unknown
Registered
2026-03-23
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild to moderate depression

Interventions

Acupuncture:Acupoints including Baihui , Yintang , Neiguan, Tianshu , Zusanli , and Taichong were selected. Acupuncture needles of 0.25×40 mm were used to perform needling to achieve deqi. The treatme
Sham acupuncture:Non-meridian and non-acupoint points on the forearms and calves were selected. Shallow needling to a depth of 2–3 mm was performed using 0.18×25 mm acupuncture needles. The treatment

Sponsors

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1) Meeting the diagnostic criteria for mild to moderate depressive episodes;2) First diagnosis, with no history of taking any antidepressant drugs, and no prior receipt of cognitive psychotherapy, physical therapy, or acupuncture therapy for depression;3) Aged 18–45 years, regardless of gender;4) Score on the 17-item Hamilton Depression Rating Scale (HAMD-17): 7 < HAMD-17 = 24;5) Suicide severity score: "No" or score < 3 points;6) Able to actively cooperate with this treatment and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1) Having any other psychiatric disorders, such as schizophrenia, bipolar affective disorder, etc.;2) Having severe liver/renal function impairment, severe arrhythmia, or cardiac insufficiency;3) Pregnant or lactating women;4) Depressive episodes caused by psychoactive substances or non-addictive substances.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Rating Scale (17-item version);

Secondary

MeasureTime frame
Hamilton Depression Rating Scale (17-item version);Hamilton Anxiety Rating Scale (14-item version);Self-Rating Depression Scale;Self-Rating Anxiety Scale;Pittsburgh Sleep Quality Index;36-Item Quality of Life Scale;

Countries

China

Contacts

Public ContactXian Jin

Affiliated Hospital of Shandong University of Traditional Chinese Medicine

doctorxianjin@163.com18853111525

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026