Diabetic Nephropathy
Conditions
Interventions
control group:basic treatment
treatment group:Basic treatment + Qijian Granules
Sponsors
China-japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1)Age: 18-75 years old, gender not limited; 2) Clearly diagnosed type 2 diabetes; Glycated hemoglobin =11%; 3) Diabetic kidney disease: eGFR: 25-75ml/min/(1.73m2) with UACR=30mg/g, or eGFR: 25 - <60 ml/min/(1.73m2) and UACR<30mg/g; And it has lasted for more than three months; 4) According to traditional Chinese medicine diagnosis, it is a syndrome of deficiency of both qi and Yin with blood stasis. 5) Sign informed consent and be able to cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1) Those with severe diabetes and those who have experienced major vascular events within half a year; 2) There are various infected individuals within 4 weeks; 3) Other traditional Chinese medicines for treating diabetic kidney diseases; 4) Pregnant or lactating women, and those who are allergic to the test drug; 5) Combined with other serious diseases, such as hematological diseases, malignant tumors, severe heart failure, and obvious liver diseases; 6) Uncontrolled hypertension (SBP=160mmHg and/or DBP=100 mmHg); 7) Patients with mental illness or those who are unable to follow along; 8) Kidney diseases that have been clearly identified as not caused by diabetes; 9) Hyperkalemia (blood potassium > 5.5mmol/L).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glomerular filtration rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urinary albumin-to-creatinine ratio;24-hour urine protein quantification;weight;waistline;blood pressure;blood fat;FBG;glycosylated hemoglobin;syndrome of Chinese medicine;quality of life; | — |
Countries
China
Contacts
Public ContactWU XIAI
China-japan Friendship Hospital, Chaoyang District, Beijing
Outcome results
None listed