Diabetic peripheral artery disease
Conditions
Interventions
Treatment group:Basic Western medicine treatment combined with Sugar Bi Capsules (4 capsules taken orally, three times a day)
blank group:Western medicine for lowering blood sugar and other basic treatments.
Sponsors
Guangdong Provincial Hospital of Traditional Chinese Medicine - University Town Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for diabetic peripheral vascular lesions; (2) Meets the diagnostic criteria for blood stasis syndrome; (3) Age between 18 and 80 years, gender; (4) Voluntarily participates in this trial and signs the informed consent form; (5) The signing of the informed consent form complies with GCP requirements.
Exclusion criteria
Exclusion criteria: (1) Patients with acute complications such as diabetic ketoacidosis, hyperglycemic hyperosmolar syndrome, diabetic lactic acidosis, or acute gout; (2) Individuals with cancer or failure of major organs such as heart, liver, or kidney; (3) Pregnant or breastfeeding individuals, or those planning pregnancy within the next year; (4) Individuals who have participated in other clinical studies within the past three months; (5) Patients who cannot understand the nature, scope, and potential outcomes of the study, or cannot follow medical instructions; (6) Patients with mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower extremity artery ultrasound; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ankle-Brachial Index (ABI);Vascular Endothelial Growth Factor (VEGF);Endothelin-1 (ET-1);Interleukin-6 (IL-6);C-reactive protein (CRP);Nitric Oxide (NO);Blood Metabolomics;Transcriptomics;Proteomics;Epigenomics;lncRNA-GAS5;miR-221-3p;HIPK2; | — |
Countries
China
Contacts
Public ContactWei Song
Guangdong Provincial Traditional Chinese Medicine University Town Branch Hospital (Endocrinology Department)
Outcome results
None listed