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A randomized controlled trial based on multi-arm multi-stage Bayesian adaptive design for screening the optimal protocol of acupoint electrical stimulation in postoperative urinary retention after anorectal surgery

Based on the "Spleen-Kidney Strengthening and Waterway Promotion" theory, this study investigates the clinical efficacy of acupuncture therapy for post-anorectal surgery urinary retention and explores the related mechanisms involving the NGF-TrkA signaling pathway.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000642
Enrollment
Unknown
Registered
2026-03-20
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-anorectal surgery urinary retention

Interventions

Electroacupuncture Group:Electroacupuncture stimulation for 30 minutes
Electroacupuncture Group:Electroacupuncture stimulation for 45 minutes
Transcutaneous Electrical Stimulation at Acupuncture Points Group:Transcutaneous acupuncture point electrostimulation for 30 minutes.
Transcutaneous Electrical Stimulation at Acupuncture Points Group:Transcutaneous acupuncture point electrostimulation for 45 minutes.
Control group (neostigmine group):Neostigmine methanesulfonate is administered via intramuscular injection into the gluteus maximus muscle, with a dosage of 1 mg.

Sponsors

Chengdu University of Traditional Chinese Medicine Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) 18 years = age = 65 years, gender unrestricted; (2) Patients who have undergone anorectal surgery and conform to the aforementioned POUR diagnostic criteria; (3) Patients with good compliance during hospitalization, capable of self-care, and willing to participate in this study; (4) Patients who have signed or had their immediate family members sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Pre-existing significant urinary dysfunction or history of urinary retention, or (such as moderate to severe benign prostatic hyperplasia with obstruction, urethral stricture, etc.); (2) Severe renal insufficiency or acute kidney injury; (3) Concurrent severe urinary tract infections, rectal malignancies, or other conditions requiring special management; (4) Allergy to acupuncture, electrical stimulation, or neostigmine, or presence of implanted devices such as pacemakers that preclude electrical stimulation; (5) (marked coagulation disorders or bleeding tendencies) that contraindicate acupuncture; (6) Pregnancy or lactation; (7) Postoperative acute hemorrhage, shock, or other severe complications; (8) Other conditions deemed unsuitable for inclusion by the investigator.

Design outcomes

Primary

MeasureTime frame
Success rate of spontaneous urination within 2 hours after the intervention (Yes/No).;

Secondary

MeasureTime frame
Time of first spontaneous voiding post-treatment;Residual urine volume in the bladder;Visual Analog Scale;

Countries

China

Contacts

Public ContactTang taichun

Chengdu University of Traditional Chinese Medicine Affiliated Hospital

634303539@qq.com17683282946

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026