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Randomized controlled trial of acupoint catgut embedding combined with lifestyle intervention to improve HOMA-IR and lipid and glucose metabolism in abdominal obesity patients with insulin resistance

Randomized controlled trial of acupoint catgut embedding combined with lifestyle intervention to improve HOMA-IR and lipid and glucose metabolism in abdominal obesity patients with insulin resistance

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000635
Enrollment
Unknown
Registered
2026-03-19
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal obesity with insulin resistance

Interventions

Fake Acupoint Thread Embedding Group:Fake Acupoint Thread Embedding

Sponsors

The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1)Meet the diagnostic criteria for abdominal obesity, body mass index (BMI) =24kg/m2; 2)HOMA-IR =2.68 and fasting blood glucose < 7.0 mmol/L; 3) The age range is 18-60 years old, regardless of sex; 4) Volunteer to participate in this study, and be able to cooperate with the collection of treatment and measurement data, and sign the informed consent. Note: Those who meet the above 4 items are included.

Exclusion criteria

Exclusion criteria: 1) Patients with secondary obesity (such as hyperthyroidism, hypothyroidism, Cushing syndrome, polycystic ovary syndrome, etc.); 2) Patients diagnosed as type 2 diabetes; 3) those who are ineffective after drug treatment or metabolic surgery; 4) Those who have taken metformin, thiazolidinedione and used other methods to lose weight in recent 3 months; 5) Complicated with serious diseases such as heart, brain, kidney, nerve and blood system; 6) Pregnant or lactating women who have pregnancy needs in the past six months; 7) All landowners allergic, scar constitution, coagulation dysfunction, allergic to collagen line; 8) Patients with mental illness and tumor, and those with communication disorder. Note: Anyone who meets any one of the above items will be excluded.

Design outcomes

Primary

MeasureTime frame
Insulin resistance index evaluated by steady-state model;

Secondary

MeasureTime frame
fasting blood-glucose;Fasting insulin;Fasting C-peptide;Glycosylated hemoglobin;Four blood lipids;C reactive protein;Tumor necrosis factor-a;Interleukin -6;weight;Body Mass Index;Body fat rate;waistline;hipline;waist hip ratio;Appetite visual analogue scale;

Countries

China

Contacts

Public ContactFeng Lin

The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine

553145017@qq.com18085181809

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026