Metabolic-associated (non-alcoholic) fatty liver disease in obesity
Conditions
Interventions
Experimental Group:Basic treatment + acupoint catgut embedding
Control Group:Basic treatment + sham acupoint embedding
Sponsors
Medical Ethics Committee of Beijing Hospital of Traditional Chinese Medicine,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age 18-65 years, any gender;2) Meets diagnostic criteria for metabolic-associated fatty liver disease;3) 24 kg/m² = BMI = 32.5 kg/m²;4) No prior acupoint catgut embedding treatment for any reason;5) Voluntarily signs informed consent.
Exclusion criteria
Exclusion criteria: 1. Metabolism related fatty liver 1) Individuals who use hepatotoxic drugs, viral hepatitis, autoimmune liver disease, hyperthyroidism, hypothyroidism, pituitary insufficiency, polycystic ovary syndrome, cirrhosis, and non-alcoholic fatty liver disease with malignant liver tumors; 2) In the past three months, there have been the following situations: weight gain or loss = 5%; Taking weight loss medication (prescription, over-the-counter, or herbal); Received acupuncture for weight loss; Participated in other weight loss projects; 3) I have undergone weight loss surgery before. 2 Health Status 1) Serious cardiovascular diseases: angina pectoris, myocardial infarction in the past 6 months, heart failure Symptomatic peripheral vascular disease; 2) Patients who have been newly diagnosed with diabetes in the past 6 months or who have adjusted hypoglycemic drugs in the past 3 months; 3) Uncontrolled thyroid disease (thyroid stimulating hormone>4.78 mIU/L or210ml/week, females>140ml/week); 3) History of drug abuse within one year; 4) History of blood donation or transfusion within one month; 5) Pregnancy or lactation, including planning to conceive within the next 3 months; 6) Allergic to absorbable surgical sutures (polyglycolic acid absorbable suture PGA); 7) According to the researcher's assessment, psychological or behavioral issues will make it difficult for them to comply with the research protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnetic Resonance Proton Density Fat Fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight;Body Mass Index;Lipid Profile (Four Items);Inflammatory markers;waist;waist-hip ratio;body fat rate;systolic blood pressure;diastolic blood pressure; | — |
Countries
China
Contacts
Public ContactWang Guiqian
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed