Diabetes
Conditions
Interventions
Experimental group:Structured exercise
Control group:Unstructured random movement
Sponsors
Hospital of Chengdu University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age between 18 and 75 years, regardless of gender; 2) Diagnosed with type 2 diabetes according to WHO criteria within the past 2 years; 3) HbA1c level between 6.5% and 9.0% (expressed as a proportion of total hemoglobin, multiplied by 0.01); 4) Body Mass Index (BMI; calculated as weight in kilograms divided by the square of height in meters) between 28-40 kg/m²; 5) Good compliance and able to be followed up for 6 months; 6) Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Presence of one or more of the following complications: severe proliferative diabetic retinopathy or worse, active foot ulcers, significant albuminuria (urine albumin-to-creatinine ratio = 300 mg/g), or renal dysfunction (eGFR = 60 ml/min/1.73m²); 2) History of cardiovascular events, including myocardial infarction, percutaneous coronary intervention, unstable angina, heart failure, and cardiac dysfunction; 3) Active viral hepatitis, AIDS, syphilis, and other sexually transmitted diseases, as well as infectious diseases such as tuberculosis; 4) Presence of exercise contraindications (e.g., severe osteoporosis, uncontrolled arthritis); 5) Cognitive impairment or mental illness that prevents participation in interventions; 6) Participation in other clinical trials within the past 3 months; 7) Other conditions that do not meet the trial criteria, such as physical disabilities or severe chronic illnesses (cancer, hypertension, etc.); 8) Currently pregnant, breastfeeding, or planning pregnancy; 9) Unstable weight in the 3 months prior to the study (weight increase or decrease > 4%); 10) Currently reporting more than 75 minutes of high-intensity exercise per week or 150 minutes of moderate-intensity exercise per week; 11) Night shift work; 12) History of eating disorders; 13) Average weekly alcohol intake: men >140g, women >70g; 14) Unsuitable for exercise if blood sugar is too high (fasting >16.7 mmol/L or random >20 mmol/L) or too low (<3.9 mmol/L), as it may trigger acute complications; 15) Any other conditions that, in the investigator's judgment, may interfere with study compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood glucose;Fasting C-peptide;Average blood glucose fluctuation;Diabetes Quality of Life Scale;Body weight;Waist circumference;Blood lipid profile test;Body fat percentage;Blood pressure;Maximum oxygen uptake;6-minute walk test distance; | — |
Countries
China
Contacts
Public ContactLiu Ya
Hospital of Chengdu University of TCM
Outcome results
None listed