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A Study Protocol on the Efficacy of Ultrasound-guided Interlaminar Epidural Injection Combined with Blood-letting Cupping Therapy for Acute Thoracolumbar Herpes Zoster-related Neuropathic Pain

A Study Protocol on the Efficacy of Ultrasound-guided Interlaminar Epidural Injection Combined with Blood-letting Cupping Therapy for Acute Thoracolumbar Herpes Zoster-related Neuropathic Pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000611
Enrollment
Unknown
Registered
2026-03-19
Start date
2025-11-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute thoracolumbar herpes zoster-associated neuropathic pain

Interventions

Observation group:On the basis of oral medications, ultrasound-guided epidural injection combined with bloodletting and cupping therapy is adopted.
Control Group:In addition to oral medications, acupuncture therapy is adopted.

Sponsors

Gao Ping People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) Meets the diagnostic criteria for "Herpes Zoster" and has herpes and pain located in the skin areas corresponding to the 1st-12th thoracic nerves and the 1st-5th lumbar nerves; 2) Disease duration is less than 1 month, in the acute phase of Herpes Zoster; 3) Age is greater than 18 years old and less than 70 years old; 4) Patient has given informed consent.

Exclusion criteria

Exclusion criteria: 1) Pregnant or breastfeeding women; 2) Neuralgia of acute herpes zoster outside the thoracolumbar spinal nerve supply area; 3) Patients with other conditions that can cause pain; 4) Patients with local skin infection, systemic infection, or coagulation disorders with a tendency to bleed; 5) Patients with severe systemic diseases (e.g., heart, brain) or a history of allergy to relevant medications; 6) Patients with renal insufficiency; 7) Patients with acute infections, spinal deformities, local anesthetic allergies, or other contraindications for epidural nerve block.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Scale (NRS) score;

Secondary

MeasureTime frame
Postherpetic Neuralgia Incidence Rate;Interleukin-6;C-reactive protein;Immunoglobulin (IgA, IgG, IgM);Pittsburgh Sleep Quality Index (PSQI);

Countries

China

Contacts

Public ContactZhang Yujia

Gao Ping People's Hospital

283596722@qq.com15582618620

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026