Urticaria
Conditions
Interventions
Acupuncture group:acupuncture treatment
Sponsors
Shanghai Research Institute of Acupuncture and Meridian
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Meets the diagnostic criteria for Chronic Urticaria (CU) according to both Traditional Chinese Medicine (TCM) and Western Medicine, and is currently in the active flare-up phase. Aged between 20 and 65 years (inclusive), regardless of gender. Demonstrates full understanding of the study, agrees to participate, and provides a signed Informed Consent Form (ICF).
Exclusion criteria
Exclusion criteria: Inducible urticaria (e.g., physical, cholinergic, aquagenic, or contact urticaria), urticaria with a clearly identifiable etiology (e.g., drug-induced or infection-related), and urticarial vasculitis. Patients with a prior history of acupuncture treatment. Use of antihistamines (e.g., ebastine, cetirizine, diphenhydramine, chlorpheniramine, promethazine, ketotifen, loratadine), glucocorticoids, or immunosuppressants within the past month. Women who are pregnant or breastfeeding. Individuals with contraindications to acupuncture, such as hemorrhagic diseases, a history of fainting during acupuncture (needle syncope), or local skin infections, ulcers, scar tissue, and tumors. Patients with psychiatric disorders or other severe systemic diseases (e.g., serious cardiac, hepatic, or renal impairment). Other patients who do not meet the inclusion criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dermatology Life Quality Index;Urticaria Control Test;Serum Immunoglobulin E;Fc epsilon receptor I alpha chain (FceRIa );Linker for activation of T cells (LAT);Spleen Tyrosine Kinase(SYK);Phosphorylated Phosphatidylinositol 3-kinase(p-PI3K);ß-N-Acetylhexosaminidase (ß-Hex); | — |
Countries
China
Contacts
Public ContactXin Zhang
Shanghai Research Institute of Acupuncture and Meridian
Outcome results
None listed