Borderline Ovarian Tumor, Ovarian Germ Cell Tumor
Conditions
Interventions
Integrated Chinese-Western Medicine Group:Western standard treatment in conjunction with Tiaozhou Yang-Tonifying / Tiaozhou Yin-Nourishing Granules.
Western Medicine (Control) Group:Western standard treatment plus placebo
Sponsors
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province People's Hospital)
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-40 years; 2. Meeting the fertility preservation criteria outlined in the Chinese Expert Consensus on Fertility-Sparing Treatment for Ovarian Malignancies and the Chinese Expert Consensus on Diagnosis and Treatment of Borderline Ovarian Tumors; 3. ECOG Performance Status score: 0-2; 4. Pathologically confirmed diagnosis of primary ovarian germ cell tumor or borderline ovarian tumor; 5. Having undergone fertility-sparing surgery; 6. Young patient with a strong desire for fertility, no other contraindications to fertility, and no contraindications to pregnancy; 7. Ability to comply with strict follow-up requirements; 8. Patient is fully informed of the treatment risks, provides informed consent, and voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. No pathological diagnosis; 2. Severe primary diseases of the heart, liver, lungs, kidneys, or hematopoietic system, or other serious conditions that affect survival; 3. Inability to provide fully informed consent; 4. Other conditions deemed unsuitable for inclusion by the investigator, such as high risk of loss to follow-up due to job relocation, etc.; 5. Patients currently participating in other clinical studies; 6. Patients requiring chemotherapy or other molecular targeted therapy before or after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ovarian reserve improvement rate;Patient Quality of Life Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor Recurrence Rate;Pregnancy Rate;Live Birth Rate;Preterm Birth/Abortion Rate; | — |
Countries
china
Contacts
Public ContactWenjun cheng
the First Affiliated Hospital of Nanjing Medical University (Jiangsu Province People's Hospital)
Outcome results
None listed