knee osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria of manipulation group 1 ) meet the diagnostic criteria of KOA, the clinical stage is early or middle ; 2 ) male or female aged 50-70 years ; 3 ) Patients with unilateral knee osteoarthritis ; 4 ) voluntarily as subjects, signed informed consent, and can receive treatment ; 5 ) good compliance, can cooperate with the completion of the score table, in accordance with the requirements of the completion of the inspection. Those who meet 5 items at the same time can be included. Control group inclusion criteria 1 ) aged 50-70 years ; 2 ) no knee pain, swelling, limited activity and other complaints and medical history ; 3 ) After clinical examination, no knee deformity, instability, normal activity and bilateral symmetry ; 4 ) body mass index ( BMI ) in the range of 18.5-28 kg / m2 ; 5 ) Voluntary to join this experiment, and signed the informed consent.
Exclusion criteria
Exclusion criteria: Manipulation group exclusion criteria 1 ) combined with other lower limb joint diseases : such as rheumatoid arthritis, ankylosing spondylitis, acute attack of gouty arthritis, history of suppurative arthritis, severe hip / ankle joint lesions, femoral head necrosis, etc. 2 ) Patients with a recent history of knee joint trauma, surgery or preparation for surgery : such as knee ligament, meniscus, fracture and other major trauma or surgery in the past 6 months. 3 ) patients with lumbar disc herniation, lumbar spinal stenosis and obvious symptoms at present ; 4 ) with severe systemic diseases : such as severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction, malignant tumors, coagulation dysfunction, etc. 5 ) Patients with neurological diseases or mental diseases : such as stroke sequelae, Parkinson 's disease, peripheral neuropathy, dementia, mental illness and so on. 6 ) Patients who are participating in other rehabilitation or drug clinical trials that may interfere with the results of this study. 7 ) unable to complete the assessment or training required for the study : if there is a serious visual impairment, hearing impairment, unable to understand the instructions. 8 ) Patients with local contraindications such as skin ulceration, infection or severe osteoporosis. Control group exclusion criteria 1 ) Previous history of major trauma and surgery of knee joint, hip joint or ankle joint ; 2 ) suffer from any known diseases that affect the biomechanics of the lower extremities, such as arthritis, peripheral neuropathy, lumbar disc herniation with lower extremity radiation pain, etc. ; 3 ) recently ( such as 3 months ) have frequently participated in high-intensity weight-bearing exercise ( such as long-distance running, basketball, football, etc. ) ; 4 ) Patients with severe heart, brain, lung and other systemic diseases, or mental diseases who could not cooperate with the examination ; 5 ) are participating in other lower limb-related clinical trials that may interfere with this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The activity of six degrees of freedom in three-dimensional motion of knee joint; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scale Score;Western Ontario and McMaster Universities Osteoarthritis Index;Kujala Score;Knee joint relaxation;Patellar laxity; | — |
Countries
China
Contacts
Guangdong Provincial Hospital of Chinese Medicine