Osteoporosis associated with benign paroxysmal positional vertigo (BPPV)
Conditions
Interventions
Treatment group:Guzhi Syrup combined with Calcium Carbonate D3 Tablets and Calcitriol Soft Capsules.
Control Group:Calcium Carbonate D3 Tablets and Calcitriol Soft Capsules.
Sponsors
Xi'an Fifth Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age between 60-80 years old; (2) Confirmed diagnosis of idiopathic BPPV with successful manual repositioning (negative Dix-Hallpike or Roll Test) after 1-2 attempts; (3) Meets diagnostic criteria for primary osteoporosis (-3.0 <= T-score <= -2.0); (4) Meets the diagnostic criteria for kidney deficiency and blood stasis pattern in traditional Chinese medicine; (5) Able to complete questionnaires and examinations; (6) Voluntarily participates and signs the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Secondary BPPV (caused by trauma, otitis media, Meniere's disease, etc.) or central vertigo; (2) Severe cervical spondylosis or fresh lumbar compression fractures that affect the implementation of treatment plans; (3) Severe cardiovascular and cerebrovascular diseases (including severe arrhythmia, acute cerebral infarction/ cerebral hemorrhage); (4) Severe hepatic or renal insufficiency, rheumatoid arthritis, hyperparathyroidism, or other diseases affecting bone metabolism; (5) Drug allergy, or recent use of medications affecting bone metabolism or cerebral vascular function; (6) Diabetic patients or patients with elevated blood glucose; (7) Unable to cooperate with cranial MRI, TCD, or bone density examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of RD;Vertigo Disability Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| TCM Syndrome Score;Bone Density;Cerebral vascular reactivity;Anterior circulation cerebral hemodynamics;Safety Index;Residual dizziness symptom changes;Serum bone metabolism status; | — |
Countries
China
Contacts
Public ContactYan Jun
Xi'an Fifth Hospital
Outcome results
None listed