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Exploring the Microcosmic Syndrome Differentiation of Traditional Chinese Medicine in the Entire Pathogenesis Chain of IPF Based on Whole Transcriptomics ceRNA Regulatory Network

Exploring the Microcosmic Syndrome Differentiation of Traditional Chinese Medicine in the Entire Pathogenesis Chain of IPF Based on Whole Transcriptomics ceRNA Regulatory Network

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2026000558
Enrollment
Unknown
Registered
2026-03-18
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic Pulmonary Fibrosis (IPF)

Interventions

Patients with IPF presenting with lung-kidney qi deficiency syndrome:None
IPF patients with lung-kidney qi deficiency syndrome complicated by blood stasis:None
IPF patients with lung-kidney qi deficiency syndrome accompanied by phlegm-heat:None
Healthy control group:None

Sponsors

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Age = 18 years old; 2) Healthy subjects meet physical examination standards; IPF patients meet disease diagnostic criteria and TCM syndrome diagnostic standards; 3) Subjects are fully informed about the study and have signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1) Concomitant other respiratory diseases that may cause coughing, wheezing, or dyspnea, such as bronchiectasis, cor pulmonale, asthma, COPD, etc.; 2) Patients with severe primary diseases of the cardiovascular, hepatic, renal, or hematopoietic systems; 3) Patients with psychiatric disorders; 4) Patients who are pregnant or breastfeeding; 5) Patients with concurrent tumors, or congenital or acquired immunodeficiency.

Design outcomes

Primary

MeasureTime frame
Differentially expressed molecules and ceRNA regulatory networks;

Countries

China

Contacts

Public ContactYang Li

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

yl18102456112@163.com18102456112

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026