sudden deafness
Conditions
Interventions
Western medicine treatment group:Conventional Western medical drug treatment
Combined treatment of Western medicine and traditional Chinese medicine group:Conventional Western medical treatment combined with TCM syndrome differentiation-based herbal medicine treatment
Combined treatment of Western medicine, TCM and acupuncture group:Conventional Western medical treatment combined with TCM syndrome differentiation-based herbal medicine treatment and TCM acupuncture
Sponsors
Shandong Second Provincial General Hospital(Shandong ENT Hospital, Shandong Institute of Otolaryngology)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1: (1) Meets the diagnosis of unilateral idiopathic sudden sensorineural hearing loss 2: (2) Disease duration = 30 days 3: (3) Age = 18 years old 4: (4) Voluntarily consents to and is able to cooperate with the completion of the study.
Exclusion criteria
Exclusion criteria: 1: (1) Patients with hemorrhagic diseases 2: (2) Patients allergic to the study drugs or with an allergic diathesis 3: (3) Patients with severe liver or kidney diseases 4: (4) Patients with mental illnesses or Alzheimer's disease who are unable to cooperate with the completion of the clinical study 5: (5) Pregnant women, lactating women, and athletes 6: (6) Patients concurrently participating in other clinical studies 7: (7) Patients who have previously received a sufficient dose of oral or intravenous hormones (prednisone 1mg/kg per day for 5 consecutive days, or methylprednisolone 40mg/dexamethasone 10mg per day for 5 consecutive days, or equivalent doses of other types of hormones converted to the aforementioned benchmark hormones) 8: (8) Patients deemed unsuitable for inclusion by the researchers (excluding those with a history of middle ear diseases, previous contralateral hearing loss, poor previous binaural hearing levels, inner ear malformations, cerebellopontine angle space-occupying lesions, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pure Tone Audiometry Threshold Average(PTA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Word Recognition Score;Tinnitus Handicap Inventory (THI);Visual Analog Scale (VAS);Dizziness Handicap Inventory (DHI); Vertigo Symptom Scale-Short Form (VSS-sf);Visual Analog Scale (VAS) for Ear Fullness/Pressure Sensation;Visual Analog Scale (VAS) for Periauricular Numbness;Insomnia Severity Index (ISI) ; Pittsburgh Sleep Quality Index (PSQI);Balanced Constitution and Unbalanced Constitution Determination Criteria Table;Traditional Chinese Medicine (TCM) Constitution Classification and Determination Table.; | — |
Countries
China
Contacts
Public ContactMingMing Wang
Shandong Second Provincial General Hospital(Shandong ENT Hospital, Shandong Institute of Otolaryngology)
Outcome results
None listed