Obesity Comorbid with Mild to Moderate Depression
Conditions
Interventions
Electroacupuncture Group:Electroacupuncture
Sham acupuncture group:sham acupuncture
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Age 18-70 years (inclusive), regardless of gender; 2.Meet Western diagnostic criteria for obesity; 3.Meet ICD-10 diagnostic criteria for mild to moderate depression; 4.Hamilton Depression Scale-17 (HAMD-17) score =8 but <24; 5.Consistent obesity and antidepressant medication regimens (in terms of dosage and type) and psychotherapy regimens for 4 weeks prior to enrollment; 6.No acupuncture or herbal treatment received within 2 weeks prior to enrollment; 7.No severe cognitive or psychiatric impairment, able to understand and complete scale assessments; 8.Patient agrees to participate, voluntarily signs informed consent, and commits to all study visits, examinations, and treatments per protocol.
Exclusion criteria
Exclusion criteria: 1.Depression suspected to be caused by other factors (e.g., medications, pregnancy) based on medical history or lab tests; 2.Secondary obesity due to endocrine, genetic, central nervous system disorders, or medications; 3.History of other psychiatric disorders; 4.Weight change >5 kg within 3 months; 5.History of organic brain injury or severe head trauma; 6.Prone to infection or bleeding; 7.Severe cardiac, hepatic, renal insufficiency, metabolic disorders, or other serious systemic diseases; 8.Severe needle phobia; 9.Participation in other clinical trials within 3 months; 10.Severe suicidal tendencies; 11.Pregnant or lactating women, or women of childbearing potential refusing contraception during the study; 12.Implanted pacemakers/defibrillators, electronic devices, or metal implants potentially affected by electrical currents; 13.Inability to adhere to lifestyle interventions; 14.Other conditions deemed unsuitable by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Montgomery–Åsberg Depression Rating Scale;Beck Depression Inventory;Clinical Global Impressions Scale (CGI);WHO Quality of Life Brief Version;blood pressure;Body Mass Index (BMI);waist;hip circumference;Waist-Hip Ratio;Body fat percentage;blood lipids;Fasting Blood Glucose;Insulin Resistance Index;Serum inflammatory factors;cortisol; | — |
Countries
China
Contacts
Public ContactLingying Huang
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed