Chronic endometritis
Conditions
Interventions
Experimental Group:Doxycycline Hyclate Tablets + Qianjin Gynecological Capsules
Control Group:Doxycycline hydrochloride tablets + Gynecological Qianjin capsule simulator
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Age range: 20 years old = age = 40 years old; 2. Meets the diagnostic criteria for chronic endometritis; 3. Meets the TCM syndrome differentiation criteria for damp-heat with deficiency of both qi and blood; 4. Has a regular menstrual cycle, with a cycle length =21 days and =35 days; 5. Voluntarily participates and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with concurrent acute genital tract and pelvic infections, etc. 2. Patients with endometrial tuberculosis, endometrial cancer, or other malignant gynecological tumors. 3. Patients with endometrial lesions, such as endometrial hyperplasia, uterine cavity adhesions, submucosal fibroids, or endometrial polyps. 4. Patients with hydrosalpinx or pelvic abscesses. 5. Patients with severe abnormalities in heart, liver, or kidney function. 6. Patients with uncontrolled autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis, etc.). 7. Patients with uncontrolled endocrine or metabolic diseases (e.g., diabetes, hyperthyroidism, or hypothyroidism, etc.). 8. Patients with mental disorders (e.g., severe depression, schizophrenia) or unable to comply with follow-up. 9. Pregnant or breastfeeding women, or those refusing contraception during treatment. 10. Patients with allergies to study drugs (including Chinese herbal components or antibiotics). 11. Patients who have participated in other clinical trials within the past 3 months. 12. Other situations where the investigator deems the patient unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The clinical efficacy rate after treatment for chronic endometritis for 56 days.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the number of CD138-positive plasma cells before and after treatment.;Efficacy rate of Traditional Chinese Medicine (TCM) syndromes after 28 and 56 days of treatment.;The changes in color Doppler ultrasound indices before and after treatment.;The clinical pregnancy rate after treatment for chronic endometritis.; | — |
Countries
China
Contacts
Public ContactXue Fengxia
Tianjin Medical University General Hospital
Outcome results
None listed