Etomidate dependence
Conditions
Interventions
Tai Chi intervention group:The preparatory exercises include 10 actions: marching in place, heel raises in standing position, parallel squat, lunge squat, crossing arm touch toes, side bending, and sh
Routine Rehabilitation Group:Delayed intervention
Sponsors
Jiangxi Normal University
Eligibility
Sex/Gender
All
Age
18 Years to 23 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for etomidate-dependent individuals (1) Age between 18–23 years old; (2) Completed physiological detoxification; (3) Diagnosed as etomidate-dependent according to the *Diagnostic and Statistical Manual of Mental Disorders (5th Edition) (DSM-V)*, with no other substance use disorders (e.g., heroin, cannabis, etc.); (4) No history of addiction to other substances except etomidate and nicotine; (5) Right-handed. 2. Inclusion criteria for healthy control group (1) Age between 18–23 years old; (2) No history of substance use; (3) Right-handed.
Exclusion criteria
Exclusion criteria: (1) Individuals with implanted metals (e.g., metallic dentures, pacemakers, etc.); (2) Patients with poorly controlled diseases; (3) Those with less than 5 months of remaining withdrawal time; (4) Individuals unwilling to participate in random allocation or with poor compliance; (5) History of mental or neurological disorders, not currently on psychotropic medications; severe mental or cognitive impairments; (6) Severe medical conditions, such as severe liver or kidney damage, chronic kidney disease, myocardial infarction, severe heart failure, or malignant tumors; (7) History of brain trauma or organic brain lesions (e.g., cerebral infarction, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Activation level of the prefrontal brain region;Reaction time and accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| The Adolescent Working Memory Scale;Pittsburgh Sleep Quality Index (PSQI);Short Form 12;Depression-Anxiety-Stress Scale 21; | — |
Countries
China
Contacts
Public ContactYao Lanxi
Jiangxi Normal University, No. 99 Ziyang Avenue, Nanchang City, Jiangxi Province
Outcome results
None listed