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Based on the Gut Microbiota and its Metabolites to explore the clinical study of Yiqiwenyang Huoxuelishui Prescription to improve the nutritional status of Chronic Heart Failure patients

Based on the Gut Microbiota and its Metabolites to explore the clinical study of Yiqiwenyang Huoxuelishui Prescription to improve the nutritional status of Chronic Heart Failure patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000522
Enrollment
Unknown
Registered
2026-03-13
Start date
2022-08-28
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Heart Failure

Interventions

Treatment group:On the basis of standardized Western medicine treatment, combining Yiqi Wenyang Huoxue Lishui Chinese herbal medicine
Control Group:Combined with a placebo on the basis of standardized Western medicine treatment.

Sponsors

Wang Jing Hospital of China Academy of Chinese Medical Sciences,Department of Cardiology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for chronic heart failure, with heart function classified as NYHA class II-IV; (2) Mini-Nutritional Assessment (MNA) score is less than 24 points; (3)Traditional Chinese medicine syndrome differentiation consistent with yang deficiency and decline, stagnant blood and water retention.; (4) Age between 18-85 years, with no restriction on gender; (5) Signed informed consent form; (Note: All the above conditions must be met simultaneously.)

Exclusion criteria

Exclusion criteria: (1) Individuals with severe cognitive dysfunction or other reasons that make communication impossible; (2) Individuals with other chronic diseases that significantly affect nutritional status, such as malignant tumors, chronic gastritis, severe liver or kidney diseases, stroke, etc.; (3) Patients deemed by the investigator to have poor compliance and unable to complete the study as required; (4) Other conditions deemed unsuitable for inclusion by the investigator. (Note: If any of the above conditions occur, the participant will be excluded.)

Design outcomes

Primary

MeasureTime frame
Mini Nutritional Assessment Scale;16S rDNA sequencing;hemoglobin;Serum total protein;Proprotein;Albumin;Triglyceride;

Countries

China

Contacts

Public ContactHuo-Yanming

Wang Jing Hospital of China Academy of Chinese Medical Sciences,Department of Cardiology

huoym98@163.com15810611873

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026