Hypomenorrhea
Conditions
Interventions
observation group:Er Xian Zelan Decoction
control group:Estradiol tablets/estradiol and progesterone tablets (2-10mg)
Sponsors
Wangjing Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Meets the Traditional Chinese Medicine (TCM) criteria for 'scanty menstruation' and the differentiation of 'kidney deficiency with blood stasis,' and meets the Western medicine diagnostic criteria for ovulatory scanty menstruation; (2) Women aged 20–40 years; (3) Experiencing scanty menstruation for three or more menstrual cycles; (4) Patients voluntarily agree to participate in this study and have signed the relevant informed consent form.
Exclusion criteria
Exclusion criteria: (1) Individuals with congenital uterine malformations or hypoplastic uterus; (2) Endometrial tuberculosis patients; (3) Individuals with severe malnutrition caused by chronic conditions such as malnutrition, malignant tumors, or other wasting diseases; (4) Patients with organic lesions such as intrauterine adhesions and massive ovarian masses; (5) Those who have used medications affecting menstruation within the past 3 months; (6) Individuals allergic to any component of the prescription medication; (7) Patients with severe primary diseases such as cardiovascular, hepatic, renal, and hematopoietic system disorders, as well as psychiatric patients; (8) Breastfeeding women or those who refuse to use contraception during the study period; (9) Individuals with intrauterine devices such as Mirena or other similar contraceptive devices; (10) Patients with active venous or arterial thromboembolic diseases within the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| menstrual flow; Traditional Chinese Medicine Syndrome Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Endometrial thickness;Uterine pulsatility index;Uterine resistance index;End Systolic Peak/End Diastolic Peak;Follicle-stimulating Hormone;luteinizing hormone;estradiol;testosterone;Anti Mullerian hormone; | — |
Countries
China
Contacts
Public ContactDING Yongfen
Wangjing Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed