Cathartic Colon
Conditions
Interventions
Chinese Medicine Treatment Group:Oral administration of Modified Qi-Regulating and Stool-Loosening Formula
Western medicine group:Oral Prucalopride Tablets
Sponsors
The Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Case Group (1) Meets the above-mentioned TCM and Western medicine diagnostic criteria for CC; (2) Male or female, aged 18–75 years; (3) No use of antibiotics, probiotics, or medications that may cause constipation within the past 3 months; (4) Agrees to participate in the study and signs the informed consent form; (5) Able to cooperate with treatment, participate in medical history inquiries, and complete relevant rating scales. Normal Control Group (1) No history of constipation or other relevant diseases; (2) Male or female, aged 18–75 years; (3) No use of antibiotics, probiotics, or medications that may cause constipation within the past 3 months; (4) Agrees to participate in the study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Both Case Group and Normal Control Group (1) Individuals with severe primary or secondary cardiovascular, cerebrovascular, renal, or other systemic diseases, metabolic disorders such as diabetes or hyperthyroidism, or psychiatric conditions; (2) Individuals diagnosed with intestinal tumors via electronic colonoscopy; (3) Individuals meeting the diagnostic criteria for constipation-predominant irritable bowel syndrome; (4) Individuals on long-term use of medications known to cause constipation; (5) Pregnant or lactating women; (6) Those with communication or cognitive impairments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete Spontaneous Bowel Movements, CSBM; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fecal consistency score;Score for the degree of difficulty in defecation;Quality of Life Assessment Scale for Constipation Patients;TCM Syndrome Scoring Table;Intestinal flora detection and short-chain fatty acid detection;Elisa method for detecting 5-HT, Ach and NE in serum; | — |
Countries
China
Contacts
Public ContactCuili Lin
The Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine
Outcome results
None listed