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The Clinical Effects of Non-pharmacological Therapy Intervention on Mild Cognitive Impairment in the Prison Population and the Characteristics of Changes in Traditional Chinese Medicine (TCM) Constitutions

The Clinical Effects of Non-pharmacological Therapy Intervention on Mild Cognitive Impairment in the Prison Population and the Characteristics of Changes in Traditional Chinese Medicine Constitutions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000499
Enrollment
Unknown
Registered
2026-03-10
Start date
2026-03-20
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment

Interventions

Shaolin Neigong Group:Participants engaged in 6 self-practice sessions per week, each lasting 60 minutes, during which they recorded their practice videos for online check-ins. Additionally, there was
Speech Therapy Group:30 people who only speak Mandarin (and/or dialects) are taught Shanghainese, and additionally, 30 people who speak Mandarin and Shanghainese are taught English.
Ear Acupoint Seed Pressing Group:The adhesive patch, which has Wangbuliuxing seeds on it, is pressed and stuck onto the acupoint.
blank group:Maintain the existing lifestyle, routine care practices, and conduct health education once a month.

Sponsors

Shanghai Hudong Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meets the diagnostic criteria for mild cognitive impairment (MCI) in Western medicine; (2) Male, aged 50-75 years; (3) Cognitive decline symptoms in MCI subjects have persisted for 3 months or longer; (4) Montreal Cognitive Assessment (MoCA) scores: =13 for illiterate individuals, =19 for those with primary education, and =24 for those with junior high school education or higher. Mini-Mental State Examination (MMSE) scores: >17 for illiterate individuals, >20 for those with primary education, and >24 for those with junior high school education or higher; (5) No treatment for mild cognitive impairment has been received in the past month, including Western medicine, traditional Chinese medicine (TCM) formulations, TCM decoctions, acupuncture, massage, cognitive-behavioral therapy, etc.; (6) No motor impairment in the upper limbs, no articulation disorders, voice disorders, or other organic speech disorders, and no uncorrected hearing impairments; (7) Proficient in Chinese, able to communicate normally, understand the content of the assessment scales, and cooperate with the treatment; (8) Voluntarily participates in this study and is willing to complete the investigation; (9) Agrees to and signs the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients who do not meet the diagnostic criteria for mild cognitive impairment in Western medicine; (2) Patients who have been clinically diagnosed with dementia (including Alzheimer's disease, vascular dementia, mixed dementia, etc.); (3) Patients with cognitive impairment caused by other diseases (e.g., Parkinson's disease, epilepsy, intracranial tumors, cranial trauma, etc.); (4) Patients with a history of stroke; (5) Patients with severe diseases, including endocrine system diseases, musculoskeletal diseases, autoimmune diseases, infectious diseases, diabetes, and other metabolic diseases; (6) Patients who need to take long-term medications that may lead to cognitive decline, such as antipsychotics, sedative-hypnotics, antihistamines, anticholinergics, theophylline, etc.; (7) Patients with a history of adult affective disorders or severe neurological deficits (e.g., various aphasia, agnosia), or currently diagnosed with schizoaffective disorder, schizophrenia, or primary adult affective disorders; (8) Patients with balance disorders or a history of severe diseases such as myasthenia gravis, knee replacement surgery, or severe lumbar disc herniation; (9) Patients currently participating in other professional cognitive intervention clinical trials that may affect the outcome evaluation of this study; (10) Patients who refuse to cooperate with this investigation.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment Scale;

Secondary

MeasureTime frame
Lawton Cognitive Assessment Scale;Traditional Chinese Medicine constitution;Mini-Mental State Examination Scale;Activities of Daily Living Scale;Blood biomarker;

Countries

China

Contacts

Public Contactqinyuan

Shanghai University of Traditional Chinese Medicine

42853536@qq.com15021337413

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026