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Mechanism of Tongren Tiaodu Acupuncture Combined with TBS Intervention in Promoting Brain Functional Remodeling in Patients with Post-Stroke Motor Aphasia

Mechanism of Tongren Tiaodu Acupuncture Combined with TBS Intervention in Promoting Brain Functional Remodeling in Patients with Post-Stroke Motor Aphasia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000484
Enrollment
Unknown
Registered
2026-03-09
Start date
2025-05-15
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Broca's Aphasia

Interventions

Basic Treatment Group:routine drug therapy, routine rehabilitation therapy, basic speech therapy
Tong Ren Therapy Treatment Group:Combined acupuncture therapy based on basic treatment
TBS Treatment Group:Combined treatment with TBS on the basis of basic therapy.
Combination Therapy Group:Based on the foundation treatment, a combined approach of Tong-Ren-Tiao-Du acupuncture and TBS therapy regimen is adopted.

Sponsors

Department of Rehabilitation Hubei Provincial Hospital of Integrated Chinese & Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Meet the aforementioned diagnostic criteria for stroke, with the lesion located in the left cerebral hemisphere. 2.Diagnosed with motor aphasia. 3.Aged between 30 and 80 years. 4.In the stroke recovery period (i.e., with a disease course of 1 to 6 months). 5.Native Mandarin speaker with an educational level of primary school or higher. 6.Absence of severe visual or auditory impairments. 7.Both the patient and their family voluntarily agree to participate in the study and have signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Patients with severe dysfunction of major organs (e.g., heart, brain), malignant tumors, or psychiatric/neurological disorders (e.g., epilepsy). 2.Patients presenting with severe impairment of consciousness or cognitive deficits. 3.Patients with contraindications to Transcranial Magnetic Stimulation (TMS) therapy (e.g., presence of metal implants within 30 cm of the treatment site, such as cochlear implants, implanted pulse generators, aneurysm clips, stents). 4.Patients with speech disorders resulting from other etiologies or pre-existing speech impairments prior to the stroke. 5.Patients with poor compliance or unwillingness to cooperate with the rehabilitation therapy.

Design outcomes

Primary

MeasureTime frame
Boston Diagnostic Aphasia Examination;Western Aphasia Battery;Functional Near-Infrared Spectroscopy;

Secondary

MeasureTime frame
National Institutes of Health Stroke Scale (NIHSS);Barthel Index;Quantitative EEG;

Countries

China

Contacts

Public ContactChen Qin

Department of Rehabilitation Hubei Provincial Hospital of Integrated Chinese & Western Medicine

13397154227@163.com133 9715 4227

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026