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Study on the Clinical Efficacy and Mechanism of Huolongguan Comprehensive Moxibustion for Cancer-Related Fatigue in Breast Cancer (Spleen-Kidney Yang Deficiency Pattern) Based on the "Gut-Immune" Axis

Study on the Clinical Efficacy and Mechanism of Huolongguan Comprehensive Moxibustion for Cancer-Related Fatigue in Breast Cancer (Spleen-Kidney Yang Deficiency Pattern) Based on the "Gut-Immune" Axis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2026000479
Enrollment
Unknown
Registered
2026-03-09
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Observation Group:Routine symptomatic treatment combined with Huolongguan comprehensive moxibustion

Sponsors

the First Hospital of Hunan University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1)Patients diagnosed with breast cancer confirmed by histopathological examination. (2)Patients accompanied by Cancer-Related Fatigue. (3)Patients currently receiving in-hospital chemotherapy, with clear consciousness, stable medical condition, and an estimated survival time of = 6 months. (4)Aged 18 to 70 years. (5)Patients (and their families) who fully understand the purpose, procedures, and risks of the study, participate voluntarily, and sign the written informed consent form.

Exclusion criteria

Exclusion criteria: (1)Patients with other concurrent primary malignancies, or those with breast cancer involving distant metastasis. (2)Patients with severe organic diseases, or poorly controlled endocrine or rheumatic immune disorders. (3)Patients with psychiatric disorders who are unable to express themselves clearly or cooperate in completing questionnaires and complying with study procedures. (4)Patients currently receiving other treatments specifically for fatigue. (5)Patients with contraindications to Huolongguan comprehensive moxibustion (e.g., skin lesions, infections, scars, or severe dermatological conditions in the treatment area).

Design outcomes

Primary

MeasureTime frame
Piper Fatigue Scale;

Secondary

MeasureTime frame
Quality of Life Questionnaire-Breast Cancer Module;Structure and composition of the gut microbiota;Immunological status;Peripheral serum inflammatory factors;Treatment adherence;Safety evaluation;TCM syndrome scores;

Countries

China

Contacts

Public ContactHe Yana

the First Hospital of Hunan University of Chinese Medicine

909932870@qq.com13875979850

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026