Acute Exacerbation of Bronchiectasis (Pattern of Phlegm-Heat Accumulation in the Lungs)
Conditions
Interventions
Sponsors
Kashgar City People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age between 18 and 75 years (inclusive) at the time of enrollment, regardless of gender; good verbal communication skills. (2) Diagnosed with bronchiectasis by modern medicine, with an acute exacerbation phase assessment, and acute onset within 3 days. (3) Patients with TCM syndrome differentiation of phlegm-heat blocking the lungs. (4) The subject has given informed consent and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Patients with allergic bronchopulmonary aspergillosis, active pulmonary tuberculosis, immunodeficiency diseases, pulmonary interstitial fibrosis, pneumothorax, pleural effusion, pulmonary embolism, ciliary dysfunction, massive hemoptysis, severe cardiovascular and cerebrovascular diseases, neurological diseases, hematological diseases, and other systemic diseases; (2) Patients with TCM syndrome differentiation belonging to cold syndrome; (3) Patients with malignant tumors; (4) Patients with hematological diseases such as leukemia, aplastic anemia, myelodysplastic syndromes, thrombocytopenia, and multiple myeloma; (5) Pregnant women or those planning to become pregnant, and lactating women; (6) Patients with severe damage to heart, liver, and kidney functions: heart function class 3-4, ALT and/or AST exceeding twice the upper limit of normal, glomerular filtration rate <60%; (7) Patients with rheumatic immune diseases who need to use glucocorticoids and immunosuppressants; (8) Patients who have received systemic glucocorticoid treatment within 2 weeks or participated in other drug clinical trials within 3 months; (9) Other situations deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sputum and Body Temperature Composite Index Scoring Table;Modified British Medical Research Council Dyspnea Scale mMRC Questionnaire Assessment Form; | — |
Secondary
| Measure | Time frame |
|---|---|
| Chinese-Mongolian Medicine Syndrome Quantification Scoring;White blood cells, neutrophil ratio, C-reactive protein (CRP), procalcitonin, blood gas analysis, inflammatory cytokine detection;Dynamic changes of chest CT;Sputum culture with drug sensitivity test; | — |
Countries
China
Contacts
Public ContactMai Mai Ti Tu Sun Yalikun
Kashgar City People's Hospital
Outcome results
None listed