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A Questionnaire Survey of Traditional Chinese Medicine Syndrome Pattern Characteristics and Multi-omics Analysis in Primary Osteoporosis

A Questionnaire Survey of Traditional Chinese Medicine Syndrome Pattern Characteristics and Multi-omics Analysis in Primary Osteoporosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2026000463
Enrollment
Unknown
Registered
2026-03-05
Start date
2025-04-24
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postmenopausal osteoporosis / senile osteoporosis

Interventions

Osteoporosis Group:questionnaire survey
50–65-year non-osteoporosis group:questionnaire survey

Sponsors

Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Females aged 50 to 80 years old, with menopause duration exceeding 1 year; 2. Agree to undergo bone density examination and detection using the tongue-pulse four-diagnosis instrument; 3. Possess reading, writing, and communication skills, and are able to cooperate with examinations and treatments; 4. Voluntarily participate in the trial and sign the informed consent form; 5. For participants selected for sample collection, the following additional criteria must be met: presence of low-energy femoral neck fracture, meeting the indications for artificial hip joint replacement surgery, scheduled for open surgery within 1 week, and kidney yang deficiency syndrome manifestations in traditional Chinese medicine diagnosis, etc.

Exclusion criteria

Exclusion criteria: 1. Participants who do not cooperate with the investigation or refuse to participate in the study midway; 2. Postmenopausal individuals due to ovariectomy or other non-natural causes and are older than 80 years; 3. Individuals with endocrine diseases affecting bone metabolism, such as parathyroid diseases, gonadal diseases, adrenal diseases, and thyroid diseases; or those who have been using long-term glucocorticoids or other medications leading to secondary osteoporosis; 4. Patients with severe cardiovascular diseases, malignant tumors with bone metastasis; 5. Participants selected for sample collection will be excluded if any of the following conditions are met: 1) Those who require surgical treatment after conservative treatment for fractures; 2) Old fractures; 3) Those with endocrine diseases, rheumatic immune system diseases, or other systemic metabolic bone diseases; 4) C-reactive protein =8 mg/L, suspected prosthetic infection; 5) Severe liver or kidney dysfunction; 6) History of uterine or ovarian surgery;

Design outcomes

Primary

MeasureTime frame
TCM Syndrome;

Secondary

MeasureTime frame
Bone Mineral Density;

Countries

china

Contacts

Public ContactMo wen

Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

657212548@qq.com15821626046

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Apr 4, 2026