Sarcopenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meets Western diagnostic criteria for sarcopenia ; 2. Aged 50-75 years, gender non-specific; 3. Capable of self-care, able to walk daily without assistive devices (e.g., crutches); 4. Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Secondary sarcopenia (caused by malignancy, severe hepatic/renal dysfunction, etc.); 2. Severe cardiovascular diseases, wasting diseases, infections, or severe osteoporosis; 3. Cognitive or mental disorders (e.g., Alzheimer's) preventing cooperation; 4. Inability to perform exercise training (joint deformity, bedridden, fractures); 5. Use of hormones or muscle relaxants within the past month; 6. Participation in other interventional trials within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short Physical Performance Battery (SPPB) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| 4-meter Gait Speed;Timed Up and Go Test ;Handgrip Strength;Performance-Oriented Mobility Assessment;Body Composition;Fatigue, Resistance, Ambulation, Illnesses, Loss of Weight Scale;Activities of Daily Living;Geriatric Depression Scale;Mini-Nutritional Assessment-short Form;Pittsburgh Sleep Quality Index;12-Item Short Form Health Survey;Serum Biomarkers; | — |
Countries
China
Contacts
Wangjing Hospital, China Academy of Chinese Medical Sciences