Acute Respiratory Distress Syndrome (ARDS)
Conditions
Interventions
Experimental Group 1:Standard care + Fusu mixture
Experimental Group 2:Standard care + Tongfu Xiefei Formula
Sponsors
Chengdu University of Traditional Chinese Medicine Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 999 Years
Inclusion criteria
Inclusion criteria: (1) ICU admission within 48 hours meeting new definition of ARDS criteria ; (2) Age =18 years; (3) Signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Known allergy to TCM components in study drugs; (2) Expected death or palliative care within 24 hours; (3) Hypoxemia primarily caused by acute heart failure, pulmonary embolism, or asthma; (4) Pregnancy or lactation; (5) Participation in other clinical trials; (6) ALT/AST >8×ULN; (7) Severe renal impairment (CrCl 12); (9) Contraindications for enteral medication (e.g., mechanical ileus); (10) History of substance abuse or mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-Day All-Cause Mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilator-free days within 28 days;Oxygenation index changes;Changes in the Sequential Organ Failure Assessment score?;Organ failure-free days within 28 days; | — |
Countries
China
Contacts
Public ContactGao Peiyang
Chengdu University of Traditional Chinese Medicine Affiliated Hospital
Outcome results
None listed