Endometriosis
Conditions
Interventions
Experimental group:Qingyu Wenshen Granules + Long-term ovulation induction IVF-ET treatment
Control group:Long-term ovulation induction IVF-ET treatment
Sponsors
Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of Western medicine for endometriosis; 2 Meet the diagnostic criteria of traditional Chinese medicine for kidney deficiency and blood stasis syndrome; 3 Meet the diagnostic criteria for infertility; 4 Age =25 years and =45 years old; 5 The menstrual cycle is regular and fluctuates between 21-35 days, and the menstrual period fluctuates between 3-7 days; 6 Women with reproductive needs; 7 Have not undergone any surgery within 3 months before participating in this study; 8. Have never undergone in vitro fertilization-frozen embryo transfer in the past; 9. Exclude male factor infertility; 10 Understand, agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Endocrine diseases, cardiovascular diseases, dyslipidemia, systemic lupus erythematosus or others Self-existing chronic ovulation disorders such as polycystic ovary syndrome, adenomyosis, and autoimmune diseases disease, human immunodeficiency virus infection, or any active infection; 2. Fallopian tube ligation and resection due to other diseases, abnormal development of the reproductive system, and infectious diseases Factors such as intrauterine adhesions and uterine malformations causing infertility; 3. Have a smoking habit (smoking in the past five years, =5 cigarettes a day); 4. Use of hormonal drugs or hormonal/non-hormonal anti-inflammatory drugs within 3 months before treatment; 5. In pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High quality embryo rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| cumulative clinical pregnancy rate;TCM Syndrome scoring form;Egg retrieval rate;Mature egg rate;Follicular fluid TNF-a content;Follicular fluid AKT1 content;Follicular fluid IL-6 content;Follicular fluid p53 content;Fertilized egg cleavage rate; | — |
Countries
China
Contacts
Public ContactYang Cao
Shanghai University of Traditional Chinese Medicine
Outcome results
None listed