Diabetic Limb Arteriosclerosis
Conditions
Interventions
Control Group:In addition to basic treatments such as dietary therapy, smoking cessation, blood sugar control, blood pressure reduction, lipid regulation, antiplatelet therapy, and appropriate exercis
Traditional Chinese Medicine Group:In the control group, on the basis of routine treatment, the Qihuang Juyu formula (Astragalus membranaceus 20g, Polygonatum sibiricum 12g, Carthamus tinctorius 12g,
Electroacupuncture Group:In the control group, on the basis of routine treatment, acupuncture was performed using 0.30×40mm acupuncture needles at bilateral Neiguan, Quchi, Hegu, Zusanli, Xuehai, and
Acupuncture-Medication Combined Group:In the control group, on the basis of routine treatment, the Qihuang Juyu formula was administered once daily, with 400ml of decoction obtained by boiling and tak
Sponsors
Hebei Provincial Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) Meets the diagnostic criteria for type 2 diabetes. (2) Belongs to the II stage of patients diagnosed with DAO according to Western medical diagnostic criteria. (3) Meets the diagnostic criteria for blood stasis syndrome in traditional Chinese medicine (TCM) differential diagnosis. (4) Aged between 40 and 70 years old. (5) Has signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Lower extremity pain, numbness, coldness, etc., caused by vascular or non-vascular diseases. (2) Patients with severe primary diseases involving organs (heart, brain, liver, kidney), hematopoietic system, endocrine system, or mental health issues. (3) Individuals with an allergic constitution or a history of allergy to any components of the study drug. (4) Women who are pregnant, breastfeeding, or intending to become pregnant. (5) Patients currently using Chinese or Western medicine for this condition or participating in other drug trials within the past two weeks. (6) Patients with significantin the TCM syndrome differentiation (blood stasis syndrome). (7) Patients with uncontrollable bleeding disorders, coagulation disorders, a tendency to bleed, or active bleeding within the past two weeks. (8) Patients who have undergone major surgery or significant trauma within the past two months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Cholesterol;Triglycerides;Low-Density Lipoprotein ;High-Density Lipoprotein;Tumor Necrosis Facto;Interleukin-1 (IL-1);Interleukin-6 (IL-6);Ankle-Brachial Index (ABI);Toe-Brachial Index (TBI);Superoxide Dismutase (SOD);Malondialdehyde (MDA);Total Antioxidant Capacity (TAC);Nitric Oxide (NO);Endothelin-1 (ET-1); | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Level in the Affected Limb;Numbness Level in the Affected Limb;Skin Temperature of the Affected Limb;Skin Color of the Affected Limb;Claudication Distance; | — |
Countries
China
Contacts
Public ContactSun Yunchao
Hebei Provincial Traditional Chinese Medicine Hospital
Outcome results
None listed