cancer related fatigue
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for breast cancer and CRF; 2. Those who have undergone radical mastectomy for breast cancer and have completed the total course of postoperative chemotherapy within one year; 3. Female patients aged 18 to 70; 4. Expected survival period =6 months; 5. Be conscious, free from mental disorders, capable of expressing personal will normally and independently completing questionnaire surveys
Exclusion criteria
Exclusion criteria: 1. Individuals who have taken other anti-fatigue drugs or received other anti-fatigue treatments within the last 1 month; 2. Those with impaired functions of vital organs; 3. Patients with recurrence, metastasis or concurrent other malignant tumors; 4. Those with skin lesions or allergies at the site of the operation; 5. Those with intellectual or mental disabilities who are unable to fill out the questionnaire and undergo the examination; 6. Pregnant and lactating women; 7. Those with contraindications to fMRI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PFS-R;rs-fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index;12-item health survey;adrenocorticotropic-hormone;Corticosterone;Hamilton Anxiety Scale;Interleukin-1ß;Interleukin-6;Tumour necrosis factor-alpha;routine blood test;renal function and liver function; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine