Knee Osteoarthritis
Conditions
Interventions
Treatment Group:Administered Yiqi Xuanbi Formula combined with basic treatment
Control Group:Administered conventional Western medicine combined with basic treatment
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients who were treated at Wangjing Hospital, China Academy of Chinese Medical Sciences between September 2020 and December 2025, with a definite diagnosis of knee osteoarthritis (KOA) recorded in the electronic medical record (EMR) system; Patients whose medical records meet the Western medical diagnostic criteria for knee osteoarthritis (in accordance with the Guidelines for the Diagnosis and Treatment of Knee Osteoarthritis) and have complete and traceable diagnostic records; Patients with a clear documentation of "qi deficiency and dampness obstruction syndrome" or equivalent syndrome descriptions in previous TCM medical records, inpatient/outpatient progress notes; Patients with imaging data (X-ray) available during treatment that can determine the Kellgren-Lawrence (K-L) grading of KOA, with a grading of Grade I to III; Patients with at least one complete set of pre-treatment and post-treatment records of primary efficacy evaluation indicators, including VAS score, WOMAC score, or TCM syndrome score; Patients with complete clinical medical records that can meet the requirements for data extraction and analysis in this study.
Exclusion criteria
Exclusion criteria: Patients with a definite diagnosis of rheumatoid arthritis, gouty arthritis, ankylosing spondylitis, infectious arthritis, or other non-degenerative knee joint diseases as documented in medical records; Patients with previous imaging or progress notes indicating severe knee structural damage (e.g., marked varus/valgus deformity, severe flexion contracture) and who have been clearly assigned to a surgical treatment pathway; Patients with severe dysfunction of vital organs such as the heart, liver, or kidneys during treatment, which may significantly affect treatment selection or efficacy evaluation; Patients with missing key study variables in medical records (e.g., incomplete records of primary efficacy indicators or treatment regimens) that preclude valid statistical analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS);Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC);TCM Syndrome Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Knee Circumference;Knee Range of MotionBlo o d; | — |
Countries
China
Contacts
Public ContactCheng Ting
Wangjing Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed