Chronic Atrophic Gastritis
Conditions
Interventions
Treatment Group:Vitamin C Tablets 100mg, three times daily (tid)+Folic Acid Tablets 5mg, twice daily (bid)+Modified Jianpi Huoxue Decoction(Pseudostellariae Radix 15g,Poria 10g,Atractylodis Macrocepha
Control Group:Vitamin C Tablets 100mg, three times daily (tid)+Folic Acid Tablets 5mg, twice daily (bid)
Sponsors
Hangzhou Linping TCM Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age: Patients aged 18 to 75 years; 2) Diagnosis of atrophic gastritis by endoscopy and histopathology (confirmed by the presence of atrophy in at least one biopsy site); 3) Negative result from a urea breath test for Helicobacter pylori (H. pylori), or a documented history of successful eradication of H. pylori with a subsequent negative test; 4) Not meeting any of the exclusion criteria.
Exclusion criteria
Exclusion criteria: 1) Severe cardiac, hepatic, or renal dysfunction. 2) History of gastric surgery. 3) History of psychiatric disorders. 4) Intake of antibiotics, acid-suppressive drugs, or gastroprotective agents within 2 weeks prior to enrollment. 5) Incomplete clinical data or misdiagnosed cases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric Mucosa Biopsy Examination;operative link for gastritis assessment(OLGA);operative link for gastric intestinal metaplasia assessment (OLGIM);Pepsinogen I ;Pepsinogen II;Graded Scoring of TCM Syndromes Symptoms;Gastrin-17; | — |
Countries
China
Contacts
Public ContactCen Gang
Hangzhou Linping TCM Hospital
Outcome results
None listed