knee osteoarthritis
Conditions
Interventions
control group:The subjects took the placebo for 90 days.
Experimental group:The subjects took the glucosamine chondroitin tablets for 90 days.
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1: 40 - 70 years old, gender not restricted. 2: Diagnosed with knee osteoarthritis: 1) Repeated knee pain within the past month, accompanied by the following two conditions, 2) Age = 50 years old, 3) Presence of bone friction sounds (feeling) during activity, 4) Morning stiffness duration = 30 minutes, 5) Kellgren & Lawrence classification: Grade 0 - III, meeting any two of the above conditions (1), 2), 3), 4), 5)). 3: Those with normal liver and kidney functions. 4: Voluntary signing of the informed consent form.
Exclusion criteria
Exclusion criteria: 1: Symptoms have worsened. Those who have taken or need to take non-steroidal anti-inflammatory drugs. 2: Individuals who are allergic to multiple medications or to the known components of the product under study. 3: Women who are pregnant or planning to get pregnant, are currently pregnant, or are in the lactation period within the past six months. 4: Diseases that affect the joints include conditions such as psoriasis, syphilitic neuropathy, xanthelasma, metabolic bone diseases, and acute trauma. 5: Patients with severe heart, brain, liver, kidney and hematopoietic system diseases, as well as those with serious occupational diseases and mental disorders. 6: Individuals who take items related to the tested function within a short period of time and whose judgment is thereby affected. 7: Those whose complaints are unclear, those with weak constitutions unable to undergo the test, and those who fail to use the test samples as per the regulations
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC Score;Clinical symptom score in traditional Chinese medicine;Kellgren & Lawrence classification; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS pain score;Inflammatory indicators (interleukin-1ß, interleukin-6, tumor necrosis factor-a); | — |
Countries
China
Contacts
Public ContactYao Jjiamei
Xiangya Hospital, Central South University
Outcome results
None listed