knee osteoarthritis
Conditions
Interventions
control group:The "Knee Osteoarthritis Health Education Manual" was distributed. A 30-minute standard health education session was received (including disease knowledge, life management, self-massage,
Fumigation group:The composition of Zhang's Formula No. 2 (Chinese knotweed 15g, Huai knotweed 15g, safflower 10g, dog spine 15g, whole angelica 15g, roasted eucommia 15g, processed 10g, immortal vine
Training group:Blood flow restriction training was conducted 10 minutes after the fumigation process. An inflatable BFR training device was used, applying pressure to the proximal part of the thigh, w
Sponsors
Fuyang Traditional Chinese Medicine Orthopedic Hospital of Hangzhou City
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age 45–75 years; 2) Meeting both the Western medicine diagnostic criteria for knee osteoarthritis and the traditional Chinese medicine diagnostic criteria for "liver-kidney deficiency syndrome"; 3) Knee X-ray examination showing Kellgren–Lawrence (K–L) grade I or II; 4) No relevant treatments that may affect the study results within 1 month prior to enrollment, including oral or topical non-steroidal anti-inflammatory drugs (NSAIDs), joint cavity aspiration, intra-articular corticosteroid or hyaluronic acid injections, etc.; 5) Voluntary participation in this study, written informed consent provided, and capable of completing the 8-week intervention and follow-up.
Exclusion criteria
Exclusion criteria: 1) Acute injuries such as meniscus or ligament damage, local fractures of the knee joint, or a history of trauma or concurrent diseases that affect the structure and function of the knee joint (such as tuberculosis, gout, tumors, rheumatoid arthritis, etc.); 2) Complicated with severe cardiovascular and cerebrovascular diseases, mental disorders, malignant tumors, liver and kidney dysfunction, or bleeding-prone diseases such as hemophilia; 3) Complicated with knee joint infection, skin wounds at the surgical site, or other skin problems that may affect the treatment; 4) Pregnant or lactating women; 5) Those with positive floating patella test; 6) Those with unstable blood sugar control; 7) Those allergic to the drugs in this study or having drug contraindications such as obstruction of lower extremity venous and lymphatic return.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC Score (Western Ontario and McMaster Universities Osteoarthritis Index); | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS);TCM Syndrome Score;Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) Score;Knee Extension Strength Measurement;Clinical Efficacy Evaluation Criteria; | — |
Countries
China
Contacts
Public ContactLuping Zhang
Fuyang Traditional Chinese Medicine Orthopedic Hospital of Hangzhou City
Outcome results
None listed