Knee osteoarthritis
Conditions
Interventions
Treatment group:Rheumatism Relief Pain-Relieving Ointment
Control Group:Lorazepam Sodium Gel Paste
Sponsors
Chongqing Dazu District Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for KOA in the 2018 edition of the Osteoarthritis Diagnosis and Treatment Guidelines; (2) Meets the diagnostic criteria for the TCM syndrome type of knee arthralgia-wind-cold-dampness arthralgia; (3) Age between 40 and 70 years, with no restriction on gender; (4) Kellgren-Lawrence imaging grading of I–III; (5) VAS score = 3; (6) No use of nonsteroidal anti-inflammatory drugs, hormones, or topical analgesics for at least 2 weeks prior to enrollment; (7) Voluntary participation and signed informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with combined rheumatic immune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, etc.; (2) Patients with severe diseases of the cardiovascular, pulmonary, hepatic, gastrointestinal, renal, hematopoietic systems, or tumors, or combined acute or chronic infections or other communicable diseases (hepatitis, tuberculosis, etc.); (3) Patients with local skin damage, infection, or unresolved trauma at the joint being studied; (4) Patients with allergies to any of the study medications; (5) Patients with a history of alcohol abuse, drug use, or neuropsychiatric abnormalities (epilepsy, depression, etc.); (6) Pregnant or breastfeeding women, or those with plans for pregnancy in the near future; (7) Patients currently participating in other clinical drug studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Intensity VAS Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| WOMAC Osteoarthritis Index;Lequesne Score; | — |
Countries
China
Contacts
Public ContactHu Hao
218, Mid-section of First Ring Road North, Longgang Subdistrict, Dazu District, Chongqing, Chief Physician
Outcome results
None listed