Carotid Atherosclerosis
Conditions
Interventions
control group:conventional therapy
Sponsors
Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Aged 40-80 years, regardless of gender; (2) Diagnostic criteria for CAS: Conform to Grade I (Carotid IMT =1.0 mm indicates AS [Atherosclerosis] with intima-media thickening) or Grade II (Carotid IMT >1.3 mm with the formation of atherosclerotic plaques, without detected arterial stenosis) as per ultrasonographic diagnostic standards; (3) Diagnosis of Qi Deficiency and Blood Stasis syndrome according to Traditional Chinese Medicine (TCM) pattern differentiation; (4) Patients and their family members are willing to cooperate and have signed the informed consent form.
Exclusion criteria
Exclusion criteria: Patients meeting any of the following criteria: (1) Patients with severe carotid artery stenosis (stenosis rate of 70%–99%) or total occlusion requiring stent implantation; (2) Patients with severe primary cerebral or pulmonary diseases, or hepatic/renal insufficiency; (3) Patients with a history of allergy to Chinese herbal medicine; (4) Patients with severe inflammatory diseases; (5) Patients with hemorrhagic diseases; (6) Patients with malignant arrhythmia; (7) Patients with a history of acute cerebrovascular events, acute coronary syndrome, or major trauma within the past 6 months; (8) Patients with hypertensive crisis or emergency; (9) Patients with psychiatric disorders; (10) Pregnant or lactating women; (11) Patients who have participated in other clinical trials within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid Plaque Area;Carotid Intima-Media Thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood Lipids;Short Form-36 Health Survey (SF-36);TCM Syndrome Scale Score; | — |
Countries
China
Contacts
Public ContactQiMao Feng
Shanghai Municipal Hospital of Traditional Chinese Medicine Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed