Postoperative nausea and vomiting
Conditions
Interventions
Control group:Dexamethasone + tropisetron
Experimental group :Dexamethasone + tropisetron + PC6 Transcutaneous Electrical Acupoint Stimulation
Sponsors
People's Hospital of Ningxia Hui Autonomous Region
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 to 85 years old, no gender limit; (2) ASA classification 1-III; (3) Patients who plan to undergo electronic bronchoscopy under general anesthesia; (4) Patients with intermediate- to high-risk PONV assessed according to the Apfel simplified scoring system (Apfel score = 2 points); (5) Sign the informed consent form before surgery and be willing to participate in this study; (6) There is no serious clinical dysfunction of heart, liver, kidney and other organs; (7) No history of drug allergy, especially allergy to dexamethasone, tropisetron or electrical stimulation equipment.
Exclusion criteria
Exclusion criteria: (1)Pregnant or lactating women; There are serious cardiovascular diseases (such as severe arrhythmia, heart failure, etc.); (2) There is a history of severe allergic reactions in the past (especially drug allergies); (3) Suffering from severe mental illness or cognitive impairment, unable to understand the research content or answer related questions; (4) Patients who are contraindicated to electrical stimulation of the Neiguan acupoint or other acupuncture treatments; (5) Patients with preoperative esophageal or gastric diseases that may affect PONV assessment (such as gastroesophageal reflux disease, severe gastric ulcers, etc.); (6) There is a history of gastrointestinal surgery before the operation or other diseases that may affect postoperative nausea and vomiting; (7) Other circumstances where clinical judgment makes participation in this study unsuitable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of Postoperative nausea and vomiting within 24 hours after surgery.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The severity of nausea and vomiting at 2 hours, 6 hours and 24 hours after the operation;The usage rate of remedial antiemetic drugs;post-anesthetic care unit (PACU) stay;Postoperative discomfort complaints (such as headache, drowsiness);Patient satisfaction score;General Information;Subjects' heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse oxygen saturation; | — |
Countries
China
Contacts
Public ContactZhu Xiaoning
People's Hospital of Ningxia Hui Autonomous
Outcome results
None listed