Heat-toxicity injuring yin syndrome diabetic foot ulcer
Conditions
Interventions
Content Group A:Oral administration of modified Gu Bu Tang combined with endovascularoplasty of the plantar arterial arch in the affected limb to fully open the plantar arch.
Group C:Oral administration of Gu Bu Tang addition and subtraction, and revascularization of the popliteal artery in the affected limb (based on preoperative objective imaging, determined to be an unr
Group B:The affected limb underwent endovascularoplasty of the plantar arterial arch, successfully opening the entire plantar arch, without the use of traditional Chinese medicine.
Sponsors
Shandong University of Traditional Chinese Medicine Affiliated Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: (1) Conform to the diagnostic criteria of heat-toxicity damaging yin in traditional Chinese medicine for gangrene; (2) Conform to the diagnostic criteria for diabetic foot in Western medicine; (3) Conform to the Wagner grading criteria for stages 2 to 4; (4) CTA confirms involvement of the anterior and/or posterior tibial arteries and the plantar arterial arch; (5) ABI = 0.5; (6) Patients with good compliance, capable of cooperating with treatment and observation.
Exclusion criteria
Exclusion criteria: (1) Patients with severe heart, liver, and kidney dysfunction; (2) Patients with malignant tumors; (3) Patients with coagulation system dysfunction and allergy to antiplatelet aggregation drugs; (4) Patients requiring amputation due to uncorrectable infections or those terminating treatment for various reasons; (5) Patients with poor blood sugar control (glycated hemoglobin >12.00%); (6) Pregnant, breastfeeding women, and special populations with mental disorders; (7) Patients who have allergic reactions or other adverse reactions to the Chinese medicine used.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound area; | — |
Secondary
| Measure | Time frame |
|---|---|
| Applied Behavior Analysis;Pain score;Blood flow filling status;Wagner grading;Diabetic Foot Quantitative Scoring in Traditional Chinese Medicine; | — |
Countries
China
Contacts
Public ContactHao Qingzhi
Shandong University of Traditional Chinese Medicine Affiliated Hospital
Outcome results
None listed