Parkinson's Disease
Conditions
Interventions
study group: the study group treated with Domdesivir tablets on the basis of conventional treatment plus warming kidney and spleen strengthening formula
control group:treated with western medicine Domdesivir tablets
Sponsors
Jiangxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: (1) Meeting the above Western medicine diagnostic criteria for Parkinson's disease, and conforming to the traditional Chinese medicine diagnostic and pattern differentiation criteria for "tremor syndrome" (essential tremor) with spleen-kidney yang deficiency pattern; (2) Aged 50–80 years, regardless of gender; (3) All cases were assessed using the Hoehn–Yahr staging scale prior to inclusion, with stages 1–3 eligible; (4) All participants voluntarily joined the trial and provided signed informed consent forms prior to enrollment.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: (1) Patients who do not meet the above diagnostic and inclusion criteria; (2) Those with a Hoehn-Yahr stage = 4; (3) Patients whose traditional Chinese medicine pattern differentiation does not correspond to spleen-kidney yang deficiency pattern; (4) Patients with cognitive impairment or severe psychiatric disorders who are unable to cooperate with the completion of the clinical trial; (5) Patients accompanied by multiple organ failure; (6) Patients with allergic constitution; (7) Those who have participated in other clinical trials within the past 3 months or are currently participating in a similar trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UPDRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| MoCA ;PDQ-39;gut microbiota; | — |
Countries
China
Contacts
Public ContactYU Ting
Jiangxi Provincial People's Hospital
Outcome results
None listed