Endometriosis
Conditions
Interventions
Control group:Dydrogesterone (China Resources, National Drug Approval Number H20213831, 2mg/day, oral).
Study group:Guizhi Fuling Pill with modifications, taken orally, one dose daily, to be taken warm in the morning and evening.
Sponsors
The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: According to Chinese and Western medical diagnostic criteria, the inclusion standards for OEM phlegm-stasis mutual entanglement syndrome are established as follows: (1) Meets Western medical diagnostic criteria for OEM; (2) Meets Chinese medical diagnostic and pattern differentiation criteria for phlegm-stasis mutual entanglement syndrome; (3) Concurrent ovarian endometriotic cysts with diameter <4cm; (4) Malignant transformation of endometriosis excluded; (5) Reproductive-age women with no desire for pregnancy within the next year or who have completed their family planning; (6) Patients requesting Chinese herbal medicine management and signing an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Concurrent malignant tumours, immune system disorders, cardiovascular or cerebrovascular diseases, chronic pulmonary conditions, abnormal liver or renal function, psychiatric disorders, gastrointestinal dysfunction, or hysterectomy, pregnancy, and lactation; (2) Patients with prior ineffective drug therapy; (3) Use of hormonal medications within three months prior to consultation (e.g., contraceptives, progestogens, GnRH-a agonists, etc.). (4) Other circumstances rendering the patient unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak pain intensity VAS score;Traditional Chinese Medicine Syndrome Scoring;The maximum diameter of the ovarian cyst; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total Duration Score for Dysmenorrhea;Overall Symptom Relief Rating;Levels of angiogenesis and tumor markers;Serum Immunological Markers and Inflammatory Cytokine Testing;Serum Hormone Level Testing;Ovarian Reserve Function Assessment; | — |
Countries
China
Contacts
Public ContactLuo xi
The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Outcome results
None listed