Chronic atrophic gastritis
Conditions
Interventions
control group:Administer placebo granules (5% active ingredient plus maltodextrin, etc.), taken as granules dissolved in water, 1 dose per day, twice daily
the treatment course is 24 weeks.
Traditional Chinese Medicine group :Administer Qilian Xiaopi traditional Chinese medicine formula granules taken as granules dissolved in water 1 dose per day twice daily
Sponsors
Wangjing Hospital China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for chronic atrophic gastritis in Western medicine and the diagnostic criteria for spleen deficiency and qi stagnation syndrome in traditional Chinese medicine; (2) HP-negative patients; (3) Pathological examination by gastroscopy before enrollment shows atrophy (reduction of the inherent glands) with or without intestinal metaplasia without mild or moderate dysplasia; (4) Aged between 35 and 70 years regardless of gender; (5) Subjects are informed and voluntarily sign the informed consent form; (6) Permanent residents of the local area able to ensure treatment follow-up; (7) No use of anticoagulants and no coagulation function disorders.
Exclusion criteria
Exclusion criteria: (1) Patients with concomitant peptic ulcers or upper gastrointestinal bleeding; (2) Patients with high-grade intraepithelial neoplasia of the gastric mucosa or pathological diagnosis suggestive of malignancy; (3) Patients with severe primary diseases; (4) Pregnant or breastfeeding women (female participants must take contraceptive measures); (5) Patients with psychiatric disorders; (6) Individuals with potential allergies to the study drug; (7) Situations deemed inappropriate for enrollment by the researcher; (8) Patients currently participating in other drug clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Self-Reported Symptom Intensity via Visual Analog Scale (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Three gastric functions;Traditional Chinese Medicine Syndrome Differentiation Scale (TCM-SDS);OLGIM and OLGA scoring criteria; | — |
Countries
China
Contacts
Public ContactTao Liu
Wangjing Hospital China Academy of Chinese Medical Sciences
Outcome results
None listed